Evidence map›Paper›PMID 29342363›Full record

ArticleAmerican journal of physiology. Cell physiology2018

Differential effects of inhibitory G protein isoforms on G protein-gated inwardly rectifying K

Muriel Nobles, David Montaigne, Sonia Sebastian, Lutz Birnbaumer, Andrew Tinker

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective effects of GαNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  4. Optogenetic Stimulation of GFrontiers in physiology · 2021
    Article
  5. GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Muriel NoblesThe Heart Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry , London , United Kingdom.ORCID 0000-0002-7654-2565
David MontaigneCentre Hospitalier Régional Universitaire de Lille , Lille , France.
Sonia SebastianThe Heart Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry , London , United Kingdom.
Lutz BirnbaumerDivision of Intramural Research, National Institute of Environmental Health Sciences , Research Triangle Park, North Carolina.
Andrew TinkerThe Heart Centre, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry , London , United Kingdom.
William Harvey Research Institute · GBInserm · FRPontificia Universidad Católica Argentina · AR

Funding

Transmembrane Signaling MechanismsZ01ES101643 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRNBAUMER, LUTZ · 2003 to 2008
$5.1M
AUTOREGULATION OF HINDLIMB BLOOD FLOWK04HL001515 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI BRITTON, STEVEN LOYAL · 1985 to 1989
–
British Heart Foundation RG/15/15/31742NIEHS NIH HHS Z01 ES101643
6 · The paper itself

Abstract

G protein-gated inwardly rectifying K

Indexed as

Ion Channel GatingAction PotentialsAnimalsArrhythmias, CardiacAtrial Function, LeftAtrial Function, RightFemaleG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein alpha Subunit, Gi2GTP-Binding Protein alpha SubunitsGTP-Binding Protein alpha Subunits, Gi-GoHeart AtriaHeart RateKineticsMaleMice, 129 StrainGnai1 protein, mouseGnai2 protein, mouseGnai3 protein, mouseG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein alpha Subunit, Gi2GTP-Binding Protein alpha SubunitsGTP-Binding Protein alpha Subunits, Gi-GoPotassiumatriaelectrophysiologyG protein-gated potassium channelinhibitory heterotrimeric G protein

Identifiers

PMID29342363
PMCPMC6008071
OpenAlexW2783245349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.