Evidence map›Paper›PMID 29342264›Full record

Observational studyThe Journal of clinical endocrinology and metabolism2018

Effect of Continuous Glucose Monitoring on Glycemic Control, Acute Admissions, and Quality of Life: A Real-World Study.

Sara Charleer, Chantal Mathieu, Frank Nobels, Christophe De Block, Regis P Radermecker, Michel P Hermans, Youri Taes, Chris Vercammen, Guy T'Sjoen, Laurent Crenier and 4 more

2 registry-linked trialsAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in The Journal of clinical endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06716671 completednot on this mapstarted 2024, after this paper: background citation

Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus

TypeobservationalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2024 to 2026Enrolled87ConditionsContinuous Glucose Monitoring, Quality of Life, Type 2 Diabetes Mellitus (T2DM)
NCT07325201 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Mitigating Diabetic Ketoacidosis in People With T1D and Chronic Kidney Disease on an SGLT1&2 Inhibitor: Ketosis Risk Factor Determination and Incorporation Into an Enhanced Glucose Ketone Report

TypeinterventionalSponsorHealthPartners InstituteRan2026 to 2030Enrolled80ConditionsType 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM), Chronic Kidney Disease, Diabetic KetoacidosisArmsSotagliflozin initiation
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Advances in Continuous Glucose Monitoring: Clinical Applications.Endocrinology and metabolism (Seoul, Korea) · 2025
    Review
  17. The role of advanced technologies in improving diabetes outcomes.The American journal of managed care · 2025
    Review
  18. Article
  19. Article
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Sara CharleerDepartment of Endocrinology, University Hospitals Leuven-Katholieke Universiteit Leuven, Leuven, Belgium.
Chantal MathieuDepartment of Endocrinology, University Hospitals Leuven-Katholieke Universiteit Leuven, Leuven, Belgium.
Frank NobelsDepartment of Endocrinology, Onze-Lieve-Vrouw Hospital Aalst, Aalst, Belgium.
Christophe De BlockDepartment of Endocrinology, Diabetology and Metabolism, University of Antwerp-Antwerp University Hospital, Antwerp, Belgium.
Regis P RadermeckerDepartment of Diabetes, Nutrition and Metabolic Disorders, Centre Hospitalier Universitaire Liege-Liege University, Liege, Belgium.
Michel P HermansDepartment of Endocrinology and Nutrition, Cliniques Universitaires St-Luc-Université Catholique de Louvain, Brussels, Belgium.
Youri TaesDepartment of Endocrinology, Algemeen Ziekenhuis Sint-Jan Brugge AV, Bruges, Belgium.
Chris VercammenDepartment of Endocrinology, Imelda Hospital Bonheiden, Bonheiden, Belgium.
Guy T'SjoenDepartment of Endocrinology, Ghent University Hospital, Ghent, Belgium.
Laurent CrenierDepartment of Endocrinology, Université Libre de Bruxelles-Hôpital Erasme, Brussels, Belgium.
Steffen FieuwsDepartment of Public Health and Primary Care, I-BioStat, KU Leuven-University of Leuven and Universiteit Hasselt, Leuven, Belgium.
Bart KeymeulenDiabeteskliniek, University Hospital Brussels-Vrije Universiteit Brussel, Brussels, Belgium.
Pieter GillardDepartment of Endocrinology, University Hospitals Leuven-Katholieke Universiteit Leuven, Leuven, Belgium.
RESCUE Trial Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Randomized controlled trials evaluating real-time continuous glucose monitoring (RT-CGM) patients with type 1 diabetes (T1D) show improved glycemic control, but limited data are available on real-world use. Objective: To assess impact of RT-CGM in real-world settings on glycemic control, hospital admissions, work absenteeism, and quality of life (QOL). Design: Prospective, observational, multicenter, cohort study. Participants: A total of 515 adults with T1D on continuous subcutaneous insulin infusion (CSII) therapy starting in the Belgian RT-CGM reimbursement program. Intervention: Initiation of RT-CGM reimbursement. Main Outcome Measure: Hemoglobin A1c (HbA1c) evolution from baseline to 12 months. Results: Between September 1, 2014, and December 31, 2016, 515 adults entered the reimbursement system. Over this period, 417 (81%) patients used RT-CGM for at least 12 months. Baseline HbA1c was 7.7 ± 0.9% (61 ± 9.8 mmol/mol) and decreased to 7.4 ± 0.8% (57 ± 8.7 mmol/mol) at 12 months (P < 0.0001). Subjects who started RT-CGM because of insufficient glycemic control showed stronger decrease in HbA1c at 4, 8, and 12 months compared with patients who started because of hypoglycemia or pregnancy. In the year preceding reimbursement, 16% of patients were hospitalized for severe hypoglycemia or ketoacidosis in contrast to 4% (P < 0.0005) the following year, with decrease in admission days from 54 to 18 per 100 patient years (P < 0.0005). In the same period, work absenteeism decreased and QOL improved significantly, with strong decline in fear of hypoglycemia. Conclusion: Sensor-augmented pump therapy in patients with T1D followed in specialized centers improves HbA1c, fear of hypoglycemia, and QOL, whereas work absenteeism and admissions for acute diabetes complications decreased.

Indexed as

Quality of LifeAdultBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHospitalizationHumansHypoglycemiaMaleMiddle AgedProspective StudiesBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID29342264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.