Evidence map›Paper›PMID 29342236›Full record

ArticleBioinformatics (Oxford, England)2018

MAGNAMWAR: an R package for genome-wide association studies of bacterial orthologs.

Corinne E Sexton, Hayden Z Smith, Peter D Newell, Angela E Douglas, John M Chaston

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Corinne E SextonDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Hayden Z SmithDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Peter D NewellDepartment of Biological Sciences, SUNY Oswego, Oswego, NY 13126, USA.
Angela E DouglasDepartment of Entomology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
John M ChastonDepartment of Plant & Wildlife Sciences, Brigham Young University, Provo, UT 84602, USA.

Funding

The protein nutrition of the symbiotic system between /Drosophila/and its gut micR01GM095372 · NIGMS · CORNELL UNIVERSITY · PI SEARLE, ANGELA E · 2011 to 2019
$2.8M
Investigation of microbial factors required for integrated functions of the DrosoF32GM099374 · NIGMS · CORNELL UNIVERSITY · PI NEWELL, PETER D · 2011 to 2013
$155k
NIGMS NIH HHS F32 GM099374NIGMS NIH HHS R01 GM095372
6 · The paper itself

Abstract

Summary: Here we report on an R package for genome-wide association studies of orthologous genes in bacteria. Before using the software, orthologs from bacterial genomes or metagenomes are defined using local or online implementations of OrthoMCL. These presence-absence patterns are statistically associated with variation in user-collected phenotypes using the Mono-Associated GNotobiotic Animals Metagenome-Wide Association R package (MAGNAMWAR). Genotype-phenotype associations can be performed with several different statistical tests based on the type and distribution of the data. Availability and implementation: MAGNAMWAR is available on CRAN. Contact: john_chaston@byu.edu.

Indexed as

Genome, BacterialSoftwareAnimalsBacteriaBacterial ProteinsGenome-Wide Association StudyMetagenomePolymorphism, Single NucleotideBacterial Proteins

Identifiers

PMID29342236
PMCPMC5972563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.