Trial reportOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2018
Multicenter US Clinical Trial With an Electric-Acoustic Stimulation (EAS) System in Adults: Final Outcomes.
Trial report in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Utility of Residual Hearing in the Cochlear Implant Ear
Subjective and Objective Performance With the SONNET2EAS
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Electrocochleography in Cochlear Implant Users with Residual Acoustic Hearing: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Influence of Electric Frequency-to-Place Mismatches on the Early Speech Recognition Outcomes for Electric-Acoustic Stimulation Users.American journal of audiology · 2023Trial
- Benefits of Cochlear Implantation in Childhood Unilateral Hearing Loss (CUHL Trial).The Laryngoscope · 2022Trial
- Nucleus Hybrid S12: Multicenter Clinical Trial Results.The Laryngoscope · 2020Trial
- Bilateral Cochlear Implants Using Two Electrode Lengths in Infants With Profound Deafness.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2019Trial
- Multi-Frequency Electrocochleography Results in Fewer Drop Alarms During Cochlear Implant Insertion.The Laryngoscope · 2026Article
- Towards a consensus on hearing and structure preservation in cochlear implantation surgery: results of the HEARRING international group survey.Frontiers in surgery · 2026Article
- A Novel Hybrid Solution for Hearing Impairments.Laryngoscope investigative otolaryngology · 2025Article
- Differences in consonant confusion patterns between bimodal cochlear implant users with greater and less bimodal advantage.Frontiers in psychology · 2025Article
- Clinical Applications of Intracochlear Electrocochleography in Cochlear Implant Users With Residual Acoustic Hearing.Journal of audiology & otology · 2024Article
- American Cochlear Implant Alliance Task Force: Recommendations for Determining Cochlear Implant Candidacy in Adults.The Laryngoscope · 2024Article
- Electro-vibrational stimulation results in improved speech perception in noise for cochlear implant users with bilateral residual hearing.Scientific reports · 2023Article
- Deep intracochlear injection of triamcinolone-acetonide with an inner ear catheter in patients with residual hearing.Frontiers in neuroscience · 2023Article
- Cochlear implant spectral bandwidth for optimizing electric and acoustic stimulation (EAS).Hearing research · 2022Article
- TMPRSS3 expression is limited in spiral ganglion neurons: implication for successful cochlear implantation.Journal of medical genetics · 2022Review
- Development and Implementation of the Cochlear Implant Quality of Life (CIQOL) Functional Staging System.The Laryngoscope · 2022Article
- Bilateral hearing aid use is feasible in patients with well-preserved hearing who struggle to acclimate to combined electro-acoustic (hybrid) stimulation.International journal of audiology · 2022Article
- Minimally Traumatic Cochlear Implant Surgery: Expert Opinion in 2010 and 2020.Journal of personalized medicine · 2022Article
- Cochlear Implant Evolving Indications: Our Outcomes in Adult Patients.Audiology research · 2022Article
- Preliminary study to determine an optimal mode for favorable residual hearing at low frequencies: Full electrical stimulation, electric acoustic stimulation, and electrical complement.Laryngoscope investigative otolaryngology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo demonstrate the safety and effectiveness of the MED-EL Electric-Acoustic Stimulation (EAS) System, for adults with residual low-frequency hearing and severe-to-profound hearing loss in the mid to high frequencies. STUDY
designProspective, repeated measures.
settingMulticenter, hospital. PATIENTS: Seventy-three subjects implanted with PULSAR or SONATA cochlear implants with FLEX electrode arrays.
interventionSubjects were fit postoperatively with an audio processor, combining electric stimulation and acoustic amplification.
main outcome measuresUnaided thresholds were measured preoperatively and at 3, 6, and 12 months postactivation. Speech perception was assessed at these intervals using City University of New York sentences in noise and consonant-nucleus-consonant words in quiet. Subjective benefit was assessed at these intervals via the Abbreviated Profile of Hearing Aid Benefit and Hearing Device Satisfaction Scale questionnaires.
resultsSixty-seven of 73 subjects (92%) completed outcome measures for all study intervals. Of those 67 subjects, 79% experienced less than a 30 dB HL low-frequency pure-tone average (250-1000 Hz) shift, and 97% were able to use the acoustic unit at 12 months postactivation. In the EAS condition, 94% of subjects performed similarly to or better than their preoperative performance on City University of New York sentences in noise at 12 months postactivation, with 85% demonstrating improvement. Ninety-seven percent of subjects performed similarly or better on consonant-nucleus-consonant words in quiet, with 84% demonstrating improvement.
conclusionThe MED-EL EAS System is a safe and effective treatment option for adults with normal hearing to moderate sensorineural hearing loss in the low frequencies and severe-to-profound sensorineural hearing loss in the high frequencies who do not benefit from traditional amplification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.