ArticleJournal of the American Geriatrics Society2018
Underdiagnosis of Influenza Virus Infection in Hospitalized Older Adults.
Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Estimating the Range and Duration of Post-influenza Symptoms, Conditions, and Diseases.Open forum infectious diseases · 2026Article
- Epidemic dynamics and age-specific distribution of respiratory pathogens: a direct-to-consumer surveillance study in four regions of China, October 2023-February 2025.BMC infectious diseases · 2026Article
- Developing Machine Learning Models Based on Clinical Manifestations to Predict Influenza - Chongqing Municipality, China, 2022-2023.China CDC weekly · 2025Article
- Creating respiratory pathogen-free environments in healthcare and nursing-care settings: a comprehensive review.GeroScience · 2025Review
- Respiratory Syncytial Virus (RSV) and Intention to Recommend RSV Vaccination: A Cross-Sectional Survey of Cardiologists and Cardiac Nurses in Southern Italy.Infectious disease reports · 2024Article
- Age Differences in Comorbidities, Presenting Symptoms, and Outcomes of Influenza Illness Requiring Hospitalization: A Worldwide Perspective From the Global Influenza Hospital Surveillance Network.Open forum infectious diseases · 2023Article
- Severe Acute Respiratory Infection-Preparedness: Protocol for a Multicenter Prospective Cohort Study of Viral Respiratory Infections.Critical care explorations · 2022Article
- Estimating excess septicaemia mortality and hospitalisation burden associated with influenza in Hong Kong, 1998 to 2019.Epidemiology and infection · 2022Article
- Incorporating Real-time Influenza Detection Into the Test-negative Design for Estimating Influenza Vaccine Effectiveness: The Real-time Test-negative Design (rtTND).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets.bioRxiv : the preprint server for biology · 2021Article
- Screening for COVID-19 in Older Adults: Pulse Oximeter vs. Temperature.Frontiers in medicine · 2021Article
- Temporal changes in short-term associations between cardiorespiratory emergency department visits and PMEnvironmental research · 2020Article
- Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults : A Cross-sectional Study.Annals of internal medicine · 2020Article
- Influenza With and Without Fever: Clinical Predictors and Impact on Outcomes in Patients Requiring Hospitalization.Open forum infectious diseases · 2020Article
- Combining Procalcitonin and Rapid Multiplex Respiratory Virus Testing for Antibiotic Stewardship in Older Adult Patients With Severe Acute Respiratory Infection.Journal of the American Medical Directors Association · 2020Article
- Evaluation of Viruses Associated With Acute Respiratory Infections in Long-Term Care Facilities Using a Novel Method: Wisconsin, 2016‒2019.Journal of the American Medical Directors Association · 2020Article
- Effect of four neuraminidase inhibitors on influenza in Osaka, Japan: An eight-year survey.Journal of general and family medicine · 2020Article
- Determinants of Fatal Outcome in Patients Admitted to Intensive Care Units With Influenza, European Union 2009-2017.Open forum infectious diseases · 2019Article
- Excess influenza hospital admissions and costs due to the 2009 H1N1 pandemic in England.Health economics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo describe factors associated with provider-ordered influenza testing in hospitalized older adults.
designInformation on participant demographics, symptoms, and provider-ordered influenza testing were collected by questionnaire and chart review. We conducted prospective laboratory-based surveillance using reverse-transcriptase polymerase chain reaction (RT-PCR), the criterion standard for diagnosis of influenza, to determine how participant characteristics and provider-ordered testing affected accurate influenza diagnosis.
settingOne academic and three community hospitals in Davidson County, Tennessee.
participantsAdults aged 18 and older with acute respiratory illness or nonlocalizing fever (N=1,422). MEASUREMENTS: We compared characteristics of participants with and without provider-ordered testing for influenza using the Wilcoxon test and Pearson chi-square test. Multivariable logistic regression models were used to identify factors predictive of provider-ordered influenza testing.
resultsTwenty-eight percent (399/1,422) of participants had provider-ordered influenza testing. Participants who were tested were younger than those not tested (58 ± 18 vs 66 ± 15, p<.001) and more likely to have influenza-like illness (ILI) (71% vs 49%, p<.001). ILI decreased with increasing age (aged 18-49, 63%; aged 50-64, 60%; aged ≥65, 48%). ILI and younger age were independent predictors of provider-ordered testing. Of the 136 participants with influenza confirmed using RT-PCR, ILI was the only significant predictor of provider-ordered testing (adjusted odds ratio=3.43, 95% confidence interval=1.22-9.70).
conclusionAdults aged 65 and older hospitalized with fever or respiratory symptoms during influenza season are less likely to undergo a provider-ordered influenza test than younger adults. Some, but not all, of this disparity is due to a lower likelihood of ILI. Further strategies are needed to increase clinician awareness and testing in this vulnerable group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.