Evidence map›Paper›PMID 29341018›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer.

Menglin Cheng, Kristine Glunde

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Menglin ChengDivision of Cancer Imaging Research, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kristine GlundeDivision of Cancer Imaging Research, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kglunde@mri.jhu.edu.
Johns Hopkins University · USSidney Kimmel Comprehensive Cancer Center · US

Funding

Theranostic Imaging of Metastatic Prostate CancerP50CA103175 · NCI · JOHNS HOPKINS UNIVERSITY · PI BARKER, PETER B · 2003 to 2015
$17.9M
Hypoxia-derived molecular MSI signatures to predict breast cancer outcomeR01CA213492 · NCI · JOHNS HOPKINS UNIVERSITY · PI GLUNDE, KRISTINE, HEEREN, RON · 2017 to 2021
$2.1M
Molecular studies of the MR-detectable oncometabolite glycerophosphocholineR01CA213428 · NCI · JOHNS HOPKINS UNIVERSITY · PI GLUNDE, KRISTINE · 2017 to 2021
$1.9M
Multi-scale Molecular Imaging of the Degradome in Breast TumorsR01CA154725 · NCI · JOHNS HOPKINS UNIVERSITY · PI GLUNDE, KRISTINE · 2011 to 2015
$1.7M
Imaging hypoxia-driven signaling pathways in the breast tumor microenvironmentR01CA134695 · NCI · JOHNS HOPKINS UNIVERSITY · PI GLUNDE, KRISTINE · 2008 to 2012
$1.5M
NCI NIH HHS P50 CA103175NCI NIH HHS R01 CA134695NCI NIH HHS R01 CA154725NCI NIH HHS R01 CA213428NCI NIH HHS R01 CA213492
6 · The paper itself

Abstract

Magnetic resonance spectroscopy (MRS) or spectroscopic imaging (MRSI) enables the detection of metabolites, amino acids, and lipids, among other biomolecules, in tumors of live mouse models of cancer. Tumor-bearing mice are anesthetized by breathing isoflurane in a magnetic resonance (MR) scanner dedicated to small animal MR. Here we describe the overall setup and steps for measuring

Indexed as

Disease Models, AnimalAnimalsBreast NeoplasmsFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceTumor Cells, CulturedXenograft Model Antitumor AssaysAmino acidAnimal setupCancerChemical shift imagingLipidMagnetic resonance spectroscopic imagingMetaboliteShimming

Identifiers

PMID29341018
PMCPMC9867917
OpenAlexW2783375451

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.