Evidence map›Paper›PMID 29340986›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Comparison of maximal Rubidium-82 activities for myocardial blood flow quantification between digital and conventional PET systems.

Joris D van Dijk, Pieter L Jager, Jochen A C van Osch, Maryam Khodaverdi, Jorn A van Dalen

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Recent Progress in Myocardial Perfusion Imaging Techniques.Nuclear medicine and molecular imaging · 2024
    Review
  3. Review
  4. Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. Effect of temporal sampling protocols on myocardial blood flow measurements using Rubidium-82 PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Activity regimes for 82Rb cardiac PET: Effects on absolute MBF and MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. The next step in improving (semi-)quantitative MPI PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  8. Value of SiPM PET in myocardial perfusion imaging using Rubidium-82.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  9. Quantification of myocardial perfusion reserve by CZT-SPECT: A head to head comparison withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  10. Effects of two patient-specific dosing protocols on measurement of myocardial blood flow with 3DEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
  11. Cardiac PET imaging: Lost in quantification. It's time to find the way.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  12. Body weight-dependent Rubidium-82 activity results in constant image quality in myocardial perfusion imaging with PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. 3D PET/CTEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Joris D van DijkDepartment of Nuclear Medicine, Isala hospital, PO Box 10400, 8000 GK, Zwolle, The Netherlands. jorisvdijk@gmail.com.ORCID 0000-0001-7514-789X
Pieter L JagerDepartment of Nuclear Medicine, Isala hospital, PO Box 10400, 8000 GK, Zwolle, The Netherlands.
Jochen A C van OschDepartment of Medical Physics, Isala hospital, Zwolle, The Netherlands.
Maryam KhodaverdiHealth Systems, Philips Benelux, Eindhoven, The Netherlands.
Jorn A van DalenDepartment of Medical Physics, Isala hospital, Zwolle, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPET-based myocardial blood flow (MBF) quantification can be inaccurate when using high tracer activities. Our aim was to derive the maximal Rubidium-82 activity for MBF assessment using a new digital PET system and compare the results with conventional analog systems.

methods1.8 GBq Rubidium-82 was injected into the cardiac insert of an anthropomorphic torso phantom. Data were acquired for 10 min using an Ingenuity TF (Philips Healthcare), Discovery 690 (D690, GE Healthcare), and digital PET prototype system (Philips Healthcare). The dynamic ranges, defined as the maximal measured activity in the reconstructed images deviating < 10% from the true present activity, were determined in all scans.

resultsThe dynamic ranges were 312 MBq for Ingenuity TF, 650 MBq for D690, and 654 MBq for digital PET prototype.

conclusionsThe maximal Rb-82 activity for MBF assessment using digital PET prototype is higher than that for its analog counterpart (Ingenuity TF), but seems comparable to the D690.

Indexed as

Image Processing, Computer-AssistedPositron-Emission TomographyRubidium RadioisotopesCoronary CirculationHumansPhantoms, ImagingReproducibility of ResultsRubidium-82Rubidium Radioisotopescardiac positron emission tomographyDigital PETdirect photon countingdynamic rangerubidium-82

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.