Evidence map›Paper›PMID 29340819›Full record

ArticleSurgical endoscopy2018

Laparoscopic liver resection for colorectal liver metastasis patients allows patients to start adjuvant chemotherapy without delay: a propensity score analysis.

Takayuki Kawai, Claire Goumard, Florence Jeune, Eric Savier, Jean-Christophe Vaillant, Olivier Scatton

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. [Evidence of minimally invasive oncological surgery of the liver].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
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  16. New frontiers in liver resection for hepatocellular carcinoma.JHEP reports : innovation in hepatology · 2020
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  17. Surgical Glove Technique for Laparoscopic Liver Resection.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takayuki KawaiDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France.
Claire GoumardDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France.
Florence JeuneDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France.
Eric SavierDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France.
Jean-Christophe VaillantDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France.
Olivier ScattonDepartment of Hepatobiliary Surgery and Liver Transplantation, Sorbonne Université, UMRS-938, Pitié-Salpêtrière Hospital, 47-83, boulevard l'hopital, 75013, Paris, France. olivier.scatton@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough adjuvant chemotherapy (AC) is widely used after liver resection (LR) for colorectal liver metastasis (CRLM), surgical invasiveness may lead to delay in starting AC, which is preferably started within 8 weeks postoperative. We investigated whether laparoscopic liver resection (LLR) for CRLM facilitates AC start without delay.

methodsBetween November 2014 and December 2016, 117 consecutive CRLM patients underwent LR followed by AC. LLR and OLR were performed in 30 and 87 patients, respectively. After propensity score matching on clinical characteristics, oncologic features, and type of resection, the time interval between liver resection and AC start was compared between LLR (n = 22) and OLR (n = 44) groups.

resultsAfter propensity score matching, major LR was performed in 8/22 (36%) and 15/44 (34%) cases of LLR and OLR groups, respectively (P = 1.0). Clinical-pathological characteristic and intraoperative findings were comparable between two groups. There was no significant difference in postoperative complications between the two groups. The time interval between liver resection and AC start was significantly shorter in LLR than in OLR group (43 ± 10 versus 55 ± 18 days, P = 0.012). While 15/44 (34%) patients started AC after 8 weeks postoperative in OLR group, all patients in LLR group started AC within 8 weeks.

conclusionsLLR for CRLM is associated with quicker return to AC when compared to OLR. The delivery of AC without delay allows CRLM patients to optimize the oncologic treatment sequence.

Indexed as

AdultAgedAged, 80 and overChemotherapy, AdjuvantColorectal NeoplasmsFemaleHepatectomyHumansLaparoscopyLiver NeoplasmsMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesAdjuvant chemotherapyColorectal cancer liver metastasisLaparoscopic liver resectionOncologic advantage

Identifiers

PMID29340819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.