Evidence map›Paper›PMID 29340792›Full record

ArticleAnnals of intensive care2018

Internal jugular vein variability predicts fluid responsiveness in cardiac surgical patients with mechanical ventilation.

Guo-Guang Ma, Guang-Wei Hao, Xiao-Mei Yang, Du-Ming Zhu, Lan Liu, Hua Liu, Guo-Wei Tu, Zhe Luo

2 registry-linked trialsAbstract read
In one paragraph

Article in Annals of intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04618419 completednot on this mapstarted 2019, after this paper: background citation

Internal Jugular Vein Sonogram Versus Electrical Cardiometry For Assessment Of Fluid Responsiveness In Adult Undergoing Coronary Artery Bypass Graft Surgery

TypeobservationalSponsorAhmed Abd El-Rahim Abd El-Hamid HammadRan2019 to 2020Enrolled40ConditionsUltrasound of IJV, Electrical CardiometryArmsinternal jugular vein distensibility index
NCT07041021 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Intraoperative Fluid Management Guided by Respiratory Variations of Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorSuez Canal UniversityRan2025 to 2026Enrolled84ConditionsPostoperative ComplicationsArmsRespiratory variation of the Internal Jugular Vein (IJV)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guo-Guang MaDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Guang-Wei HaoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Xiao-Mei YangDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Du-Ming ZhuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Lan LiuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Hua LiuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China.
Guo-Wei TuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China. tu.guowei@zs-hospital.sh.cn.
Zhe LuoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, Xuhui District, People's Republic of China. luo.zhe@zs-hospital.sh.cn.

Funding

Health and Family Planning Commission of Shanghai 20154Y011National Natural Science Foundation of China 81500067Natural Science Foundation of Shanghai 16ZR1405600Research Funds of Zhong Shan Hospital 2016ZSQN23Research Funds of Zhong Shan Hospital 2017ZSYXQN23
6 · The paper itself

Abstract

backgroundTo evaluate the efficacy of using internal jugular vein variability (IJVV) as an index of fluid responsiveness in mechanically ventilated patients after cardiac surgery.

methodsSeventy patients were assessed after cardiac surgery. Hemodynamic data coupled with ultrasound evaluation of IJVV and inferior vena cava variability (IVCV) were collected and calculated at baseline, after a passive leg raising (PLR) test and after a 500-ml fluid challenge. Patients were divided into volume responders (increase in stroke volume ≥ 15%) and non-responders (increase in stroke volume < 15%). We compared the differences in measured variables between responders and non-responders and tested the ability of the indices to predict fluid responsiveness.

resultsThirty-five (50%) patients were fluid responders. Responders presented higher IJVV, IVCV and stroke volume variation (SVV) compared with non-responders at baseline (P < 0.05). The relationship between IJVV and SVV was moderately correlated (r = 0.51, P < 0.01). The areas under the receiver operating characteristic (ROC) curves for predicting fluid responsiveness were 0.88 (CI 0.78-0.94) for IJVV compared with 0.83 (CI 0.72-0.91), 0.97 (CI 0.89-0.99), 0.91 (CI 0.82-0.97) for IVCV, SVV, and the increase in stroke volume in response to a PLR test, respectively.

conclusionsUltrasound-derived IJVV is an accurate, easily acquired noninvasive parameter of fluid responsiveness in mechanically ventilated postoperative cardiac surgery patients, with a performance similar to that of IVCV.

Indexed as

Cardiac surgeryFluid responsivenessInferior vena cavaInternal jugular veinsStroke volume variation

Identifiers

PMID29340792
PMCPMC5770347

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.