Evidence map›Paper›PMID 29340776›Full record

ArticleActa neurochirurgica2018

Ectopic Cushing's syndrome secondary to olfactory neuroblastoma.

Kenny Yu, Federico Roncaroli, Tara Kearney, David Ewins, Deepa Beeharry, Thomas Naylor, David Ray, Rajiv Bhalla, Kanna Gnanalingham

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neurochirurgica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis.Journal of the Egyptian National Cancer Institute · 2024
    Article
  2. Exclusively endoscopic surgical resection of esthesioneuroblastoma: A systematic review.World journal of otorhinolaryngology - head and neck surgery · 2022
    Review
  3. Comparison of diagnostic efficacy ofFrontiers in endocrinology · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kenny YuDepartment of Neurosurgery, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, M6 8HD, UK. Kenny.yu@srft.nhs.uk.ORCID 0000-0002-2394-4990
Federico RoncaroliDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, School of Biological Science, University of Manchester, Manchester, M13 9PT, UK.
Tara KearneyDepartment of Endocrinology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, M6 8HD, UK.
David EwinsDepartment of Endocrinology, Countess of Chester Hospital, Liverpool Road, Chester, CH2 1UL, UK.
Deepa BeeharryDepartment of Endocrinology, Countess of Chester Hospital, Liverpool Road, Chester, CH2 1UL, UK.
Thomas NaylorDepartment of Endocrinology, Countess of Chester Hospital, Liverpool Road, Chester, CH2 1UL, UK.
David RayDepartment of Endocrinology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, M6 8HD, UK.
Rajiv BhallaDepartment of Otorhinolaryngology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, M6 8HD, UK.
Kanna GnanalinghamDepartment of Neurosurgery, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, M6 8HD, UK.
Manchester Academic Health Science Centre · GBUniversity of Liverpool · GBUniversity of Manchester · GB

Funding

Medical Research Council MR/L00254X/1Medical Research Council MR/L010240/1Medical Research Council MR/P011853/1Wellcome Trust 107851/Z/15/Z
6 · The paper itself

Abstract

We present the case of a patient with Cushing's syndrome secondary to ectopic ACTH secretion. A MR of the head showed a left-sided nasal mass extending down from the cribriform plate. The patient underwent endoscopic resection with nearly complete removal of the mass. Histological examination showed an ACTH-secreting olfactory neuroblastoma (ONB). The patient's cortisol levels returned to normal range after surgery and have remained normal for over a year. ONB is a rare cause for ectopic ACTH secretion. This case highlights the diagnostic and management difficulties in patients with ectopic ACTH secretion, and provides a brief review of ONB.

Indexed as

Cushing SyndromeEsthesioneuroblastoma, OlfactoryHumansMaleMiddle AgedNose NeoplasmsACTHCushing’sEctopicOlfactory neuroblastoma

Identifiers

PMID29340776
PMCPMC5897482
OpenAlexW2782888030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.