ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2019
Risk factors for early infection following hemiarthroplasty in elderly patients with a femoral neck fracture.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Factors Associated With Surgical Site Infections in Adults Following a Replacement of Weight-Bearing Joints: A Systematic Review.International wound journal · 2026Pooled it
- Risk prediction models for postoperative infections in patients with hip fractures: a systematic review and critical appraisal.Frontiers in medicine · 2026Pooled it
- Beyond the Surgery: Determinants of Infection, Dislocation, and Revision After Hip Hemiarthroplasty.Cureus · 2025Article
- Differences in acute phase pain characteristics between patients undergoing bipolar hip arthroplasty versus open reduction internal fixation for hip fracture.Archives of orthopaedic and trauma surgery · 2025Article
- Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany.Patient safety in surgery · 2024Article
- C-reactive protein during the first 6 postoperative days after total hip arthroplasty cannot predict early periprosthetic infection.Archives of orthopaedic and trauma surgery · 2023Article
- Early hip fracture surgery is safe for patients on direct oral anticoagulants.OTA international : the open access journal of orthopaedic trauma · 2023Article
- Do Elevated Serum C-Reactive-Protein Levels Excuse Delayed Surgery for Femoral Neck Fractures?Antibiotics (Basel, Switzerland) · 2023Article
- Surgical-site infection after hip fracture surgery: preoperative full-body disinfection compared to local disinfection of the surgical site-a population-based observational cohort study.European geriatric medicine · 2022Observational
- Reduction of early surgical site and other care related infections in 3553 hip fracture patients: lessons learned from the 5-year Safe Hands project.Antimicrobial resistance and infection control · 2022Observational
- Identification of risk factors for surgical site infection after type II and type III tibial pilon fracture surgery.World journal of clinical cases · 2022Article
- Effects of SARS-CoV‑2 infections on inpatient mortality of geriatric patients after proximal femoral fracture surgery.Orthopadie (Heidelberg, Germany) · 2022Article
- Retrospective Study from a Single Center to Identify Risk Factors Associated with Reinfection in Patients Undergoing 2-Stage Revision Surgery for Periprosthetic Joint Infection.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Hip resection arthroplasty for acute femoral neck fractures in the non-ambulator.OTA international : the open access journal of orthopaedic trauma · 2022Article
- Antibiotic prophylaxis as a quality of care indicator: does it help in the fight against surgical site infections following fragility hip fractures?Archives of orthopaedic and trauma surgery · 2022Article
- Effect of nHA-Coated Femoral Stem Prosthesis Combined with Platelet-Rich Plasma in Hemi Hip Replacement of Femoral Neck Fracture in the Elderly.Computational and mathematical methods in medicine · 2022Article
- Management of pertrochanteric fractures in patients over 90 years: In-hospital mortality rate, complications and associated risk factors.BMC musculoskeletal disorders · 2021Article
- Preoperative C-reactive protein and other inflammatory markers as predictors of postoperative complications in patients with colorectal neoplasia.World journal of surgical oncology · 2021Article
- Significance of nutritional status in the development of periprosthetic infections : A retrospective analysis of 194 patients.Der Orthopade · 2021Article
- Treatment effect of elastic intramedullary nail reduction and fixation on children with femoral neck fractures.American journal of translational research · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePeriprosthetic joint infections (PJI) after hemiarthroplasty for geriatric femoral neck fractures are a devastating complication that results in serious morbidity and increased mortality. Identifying risk factors associated with early infection after HA for hip fractures may offer an opportunity to address and prevent this complication in many patients. The aim of this study was to evaluate preoperative risk factors for early PJI after HA in hip fracture patients.
methodsFrom January 2010 to December 2015, 312 femoral neck fractures (AO/OTA 31-B) in 305 patients were included in this single-center, retrospective study. PJI was defined according to the Centers for Disease Control (CDC) definition of deep incisional surgical site infection. Early infection referred to a postoperative period of 4 weeks. Binary univariable and multivariable regression analysis with backward elimination was applied to identify predictors of PJI.
resultsMedian age of all patients was 83.0 (IQR 76-89) years. We identified 16 (5.1%) early PJI which all required surgical revision. Median length of in-hospital stay (LOS) was 20.0 (IQR 10-36) days after PJI compared to 10.0 (8-15) days without deep wound infection. In-hospital mortality was 30.8 vs. 6.6%, respectively. Preoperative CRP levels (OR 1.009; 95% CI 1.002-1.018; p = 0.044), higher BMI (OR 1.092; 95% CI 1.002-1.189; p = 0.044) and prolonged surgery time (OR 1.013; 95% CI 1.000-1.025; p = 0.041) were independent risk factors for PJI. Excluding infection following major revision due to mechanical complications identified preoperative CRP levels (OR 1.012; 95% CI 1.003-1.021; p = 0.007) and chronic glucocorticoid therapy (OR 6.314; 95% CI 1.223-32.587; p = 0.028) as risk factors, a clear trend was seen for higher BMI (OR 1.114; 95% CI 1.000-1.242; p = 0.051). A cut-off value at CRP levels ≥ 14 mg/l demonstrated a sensitivity of 69% and a specificity of 70% with a fair accuracy (AUC 0.707).
conclusionPreoperative serum CRP levels, higher BMI and prolonged surgery time are independent predictors of early PJI. Excluding PJI secondary to major revision surgery revealed chronic glucocorticoid use as a risk factor apart from preoperative CRP levels.
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