Evidence map›Paper›PMID 29340553›Full record

ReviewArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery

HEPATOCELLULAR CARCINOMA: DIAGNOSIS AND OPERATIVE MANAGEMENT.

Marcio F Chedid, Cleber R P Kruel, Marcelo A Pinto, Tomaz J M Grezzana-Filho, Ian Leipnitz, Cleber D P Kruel, Leandro A Scaffaro, Aljamir D Chedid

Open access · diamondAbstract readReview
In one paragraph

Review in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 132 citations in OpenAlex.

  1. Trial
  2. Trial
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  4. Observational
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  7. Circulating tumor DNA and its role in detection, prognosis and therapeutics of hepatocellular carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
    Article
  8. Article
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  11. Review
  12. Article
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  17. CharacterizingJournal of oncology · 2022
    Article
  18. New approach for hepatocellular carcinoma treatment.Journal of medicine and life · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Marcio F ChedidPostgraduate Program in Surgical Sciences.
Cleber R P KruelUnit of Hepatobiliary Surgery and Liver and Pancreas Transplantation, Division of Gastrointestinal Surgery.
Marcelo A PintoUnit of Hepatobiliary Surgery and Liver and Pancreas Transplantation, Division of Gastrointestinal Surgery.
Tomaz J M Grezzana-Filho
Ian Leipnitz
Cleber D P KruelPostgraduate Program in Surgical Sciences.
Leandro A ScaffaroInterventional Radiology Unit, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Aljamir D ChedidUnit of Hepatobiliary Surgery and Liver and Pancreas Transplantation, Division of Gastrointestinal Surgery.
Second Military Medical University · CNEastern Hepatobiliary Surgery Hospital · CNUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatocellular carcinoma is an aggressive malignant tumor with high lethality.

aimTo review diagnosis and management of hepatocellular carcinoma.

methodsLiterature review using web databases Medline/PubMed.

resultsHepatocellular carcinoma is a common complication of hepatic cirrhosis. Chronic viral hepatitis B and C also constitute as risk factors for its development. In patients with cirrhosis, hepatocelular carcinoma usually rises upon malignant transformation of a dysplastic regenerative nodule. Differential diagnosis with other liver tumors is obtained through computed tomography scan with intravenous contrast. Magnetic resonance may be helpful in some instances. The only potentially curative treatment for hepatocellular carcinoma is tumor resection, which may be performed through partial liver resection or liver transplantation. Only 15% of all hepatocellular carcinomas are amenable to operative treatment. Patients with Child C liver cirrhosis are not amenable to partial liver resections. The only curative treatment for hepatocellular carcinomas in patients with Child C cirrhosis is liver transplantation. In most countries, only patients with hepatocellular carcinoma under Milan Criteria are considered candidates to a liver transplant.

conclusionHepatocellular carcinoma is potentially curable if discovered in its initial stages. Medical staff should be familiar with strategies for early diagnosis and treatment of hepatocellular carcinoma as a way to decrease mortality associated with this malignant neoplasm.

Indexed as

AlgorithmsCarcinoma, HepatocellularHepatectomyHumansLiver Neoplasms

Identifiers

PMID29340553
PMCPMC5793147
OpenAlexW2783634552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.