ArticleKidney international reports2018
Location-Specific Oral Microbiome Possesses Features Associated With CKD.
Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Advances in the study of oral microbiota and metabolism associated fatty liver disease: a systematic review.Frontiers in cellular and infection microbiology · 2024Pooled it
- Oral microbiota mediates the association of healthy dietary patterns with lower risk of advanced cardiovascular-kidney-metabolic syndrome.Nutrition & diabetes · 2026Article
- Article
- Association of periodontitis with reduced kidney function and albuminuria in early chronic kidney disease: a population-based study.International journal of oral science · 2026Article
- Causal association between oral microbiome and chronic kidney disease: two-sample Mendelian randomization.Archives of medical science : AMS · 2026Article
- Oral microbiota and urinary system diseases: from mechanistic insights to clinical implications-a comprehensive review.Frontiers in dental medicine · 2026Review
- Oral Health Assessment in Adolescents with End-Stage Chronic Kidney Disease.Journal of clinical medicine · 2025Article
- Unraveling the oral microbiome's role in Alzheimer's disease: From pathophysiology to therapeutic potential.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Integrative insights into the oral microbiome's role in systemic diseases: novel therapeutic strategies and future directions.Antonie van Leeuwenhoek · 2025Review
- Microbiota and kidney disease: the road ahead.Nature reviews. Nephrology · 2025Review
- Comparative Evaluation of Tongue and Periodontal Pocket Microbiome in Relation toAntibiotics (Basel, Switzerland) · 2025Article
- Oral dysbiosis initiates periodontal disease in experimental kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Characteristics of tongue coating microbiota in diabetic and non-diabetic kidney patients receiving hemodialysis.BMC oral health · 2025Article
- Correlation of tongue coating thickness with microinflammatory state and oral microbiome in maintenance hemodialysis patients.Journal of oral microbiology · 2025Article
- Salivary microbiome in peritoneal dialysis patients with and without sarcopenia: A pilot study.PloS one · 2025Article
- The profile of oral microbiome in Chinese elderly population associated with aging and systemic health status.BMC oral health · 2024Article
- Prediction of delayed graft function by early salivary microbiota following kidney transplantation.Applied microbiology and biotechnology · 2024Article
- Oro-Respiratory Dysbiosis and Its Modulatory Effect on Lung Mucosal Toxicity during Exposure or Co-Exposure to Carbon Nanotubes and Cigarette Smoke.Nanomaterials (Basel, Switzerland) · 2024Article
- Review
- Association between salivary microbiota and renal function in renal transplant patients during the perioperative period.Frontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
introductionChronic kidney disease (CKD), a progressive loss of renal function, can lead to serious complications if underdiagnosed. Many studies suggest that the oral microbiota plays important role in the health of the host; however, little is known about the association between the oral microbiota and CKD pathogenesis.
methodsIn this study, we surveyed the oral microbiota in saliva, the left and right molars, and the anterior mandibular lingual area from 77 participants (18 with and 59 without CKD), and tested their association with CKD to identify microbial features that may be predictive of CKD status.
resultsThe overall oral microbiota composition significantly differed by oral locations and was associated with CKD status in saliva and anterior mandibular lingual samples. In CKD patients, we observed a significant enrichment of
conclusionWe demonstrate the association of the oral microbiome with CKD and inflammatory kidney biomarkers, highlighting a potential role of the commensal bacteria in CKD pathogenesis. A better understanding of the interplay between the oral microbiota and CKD may help in the development of new strategies to identify at-risk individuals or to serve as a novel target for therapeutic intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.