Evidence map›Paper›PMID 29340318›Full record

ArticleKidney international reports2018

Michael D Hughson, Wendy E Hoy, Susan A Mott, John F Bertram, Cheryl A Winkler, Jeffrey B Kopp

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Journal of the American Society of Nephrology : JASN · 2019
    Pooled it
  2. Update on APOL1 and chronic kidney diseases in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Article
  4. Review
  5. Arteriosclerosis, thrombosis, and vascular biology · 2021
    Article
  6. Article
  7. Review
  8. Ten years in: APOL1 reaches beyond the kidney.Current opinion in nephrology and hypertension · 2019
    Review
  9. Article
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Michael D HughsonDepartment of Pathology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Wendy E HoyCentre for Chronic Disease, The University of Queensland, Brisbane, Queensland, Australia.
Susan A MottCentre for Chronic Disease, The University of Queensland, Brisbane, Queensland, Australia.
John F BertramCardiovascular Program Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia.
Cheryl A WinklerBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Inc., Frederick National Laboratory, Frederick, Maryland, USA.
Jeffrey B KoppKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland, USA.
University of Queensland · AUCenter for Cancer Research · USMonash University · AUNational Institutes of Health · USUniversity of Mississippi Medical Center · US

Funding

Focal Segmental Glomerulosclerosis: Genetics & MechanismsZIADK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$15.7M
Genetics of Renal Disease in African AmericansZIABC010022 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINKLER, CHERYL · 2009 to 2022
$8.9M
Nephron Count, Birth Weight &Hypertensive Renal DiseaseR01DK065970 · NIDDK · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI HUGHSON, MICHAEL DONALD · 2004 to 2006
$659k
NIDDK NIH HHS R01 DK065970
6 · The paper itself

Abstract

introductionThe relationship of

methodsAge, cause of death, and nephrosclerosis (the latter defined by glomerulosclerosis) were analyzed in the autopsies of 162 African Americans and 136 whites genotyped for

resultsSudden deaths represented >75% of CVD autopsies for both races and all-risk genotypes. The average ages of CVD deaths for African Americans with 1 and 2

conclusionCarriage of 1 or 2

Indexed as

APOL1cardiovascular diseasehypertensionnephrosclerosisrace

Identifiers

PMID29340318
PMCPMC5762961
OpenAlexW2749430885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.