ReviewKidney international reports2018
Treatment of Severe Hyperkalemia: Confronting 4 Fallacies.
Review in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Pharmacological Nephroprotection in Chronic Kidney Disease Patients with Type 2 Diabetes Mellitus-Clinical Practice Position Statement of the Polish Society of Nephrology.International journal of molecular sciences · 2024Guideline
- Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology.Journal of nephrology · 2019Guideline
- Emergency Potassium Normalization Treatment Including Sodium Zirconium Cyclosilicate: A Phase II, Randomized, Double-blind, Placebo-controlled Study (ENERGIZE).Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2020Trial
- Emergency management of hyperkalemia in dogs and cats - Part 2: Diagnosis and treatment.The Canadian veterinary journal = La revue veterinaire canadienne · 2026Review
- [Consensus recommendations on the diagnosis and treatment of hyperkalemia of the Austrian Society of Nephrology 2026].Wiener klinische Wochenschrift · 2026Review
- Article
- Monitoring serum potassium concentration in patients with severe hyperkalemia: the role of bloodless artificial intelligence-enabled electrocardiography.Clinical kidney journal · 2025Article
- Case Report: Inhaled salbutamol in the successful treatment of life-threatening acute hyperkalaemia in an anaesthetised horse.Frontiers in veterinary science · 2025Article
- Management of hyperkalemia: Expert consensus from Kuwait - a Modified Delphi Approach.International journal of nephrology and renovascular disease · 2024Article
- Is There a Clinically Relevant Risk of Hyperkalemia with Topical Clascoterone Treatment?The Journal of clinical and aesthetic dermatology · 2023Review
- Article
- Treatment strategies for hyperkalemia secondary to urethral obstruction in 50 male cats: 2002-2017.Journal of feline medicine and surgery · 2022Article
- Hyperkalaemia in Heart Failure: Consequences for Outcome and Sequencing of Therapy.Current heart failure reports · 2022Review
- Hyperkalemia in Chronic Kidney Disease: Links, Risks and Management.International journal of nephrology and renovascular disease · 2022Review
- Low dialysis potassium bath is associated with lower mortality in end-stage renal disease patients admitted to hospital with severe hyperkalemia.Clinical kidney journal · 2021Article
- Hyperkalemia: A persisting risk. A case report and update on current management.Clinical case reports · 2020Article
- Hemodialysis treatment in patients with severe electrolyte disorders: Management of hyperkalemia and hyponatremia.Hemodialysis international. International Symposium on Home Hemodialysis · 2020Review
- Severe Hyperkalemia Immediately After Birth.The American journal of case reports · 2019Article
- Pharmacologic Treatment of Chronic Hyperkalemia in Patients with Chronic Kidney Disease.Electrolyte & blood pressure : E & BP · 2019Review
- Chronic Kidney Disease and Dietary Measures to Improve Outcomes.Pediatric clinics of North America · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe hyperkalemia is a medical emergency that can cause lethal arrhythmias. Successful management requires monitoring of the electrocardiogram and serum potassium concentrations, the prompt institution of therapies that work both synergistically and sequentially, and timely repeat dosing as necessary. It is of concern then that, based on questions about effectiveness and safety, many physicians no longer use 3 key modalities in the treatment of severe hyperkalemia: sodium bicarbonate, sodium polystyrene sulfonate (Kayexalate [Concordia Pharmaceuticals Inc., Oakville, ON, Canada], SPS [CMP Pharma, Farmville, NC]), and hemodialysis with low potassium dialysate. After reviewing older reports and newer information, I believe that these exclusions are ill advised. In this article, I briefly discuss the treatment of severe hyperkalemia and detail why these modalities are safe and effective and merit inclusion in the treatment of severe hyperkalemia.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.