Evidence map›Paper›PMID 29340252›Full record

ArticlePeerJ2018

Positive selection on human gamete-recognition genes.

Michael W Hart, Daryn A Stover, Vanessa Guerra, Sahar V Mozaffari, Carole Ober, Carina F Mugal, Ingemar Kaj

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Sexual selection and pseudogenization in primate fertilization.Evolution; international journal of organic evolution · 2025
    Article
  2. Digital Image Processing to Detect Adaptive Evolution.Molecular biology and evolution · 2024
    Article
  3. Article
  4. Article
  5. Article
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  7. Molecular mechanisms and evolution of fertilization proteins.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Egg Coat Proteins Across Metazoan Evolution.Current topics in developmental biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Michael W HartDepartment of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Daryn A StoverSchool of Mathematical and Natural Sciences, Arizona State University Colleges at Lake Havasu City, Lake Havasu City, AZ, USA.
Vanessa GuerraDepartment of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Sahar V MozaffariDepartment of Human Genetics, University of Chicago, Chicago, IL, USA.
Carole OberDepartment of Human Genetics, University of Chicago, Chicago, IL, USA.
Carina F MugalDepartment of Ecology and Genetics, Uppsala University, Uppsala, Sweden.
Ingemar KajDepartment of Mathematics, Uppsala University, Uppsala, Sweden.
Simon Fraser University · CAUniversity of Chicago · USUppsala University · SEArizona State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coevolution of genes that encode interacting proteins expressed on the surfaces of sperm and eggs can lead to variation in reproductive compatibility between mates and reproductive isolation between members of different species. Previous studies in mice and other mammals have focused in particular on evidence for positive or diversifying selection that shapes the evolution of genes that encode sperm-binding proteins expressed in the egg coat or zona pellucida (ZP). By fitting phylogenetic models of codon evolution to data from the 1000 Genomes Project, we identified candidate sites evolving under diversifying selection in the human genes

Indexed as

Balancing selectionEpistasisFertilizationLinkage disequilibriumZona pellucida

Identifiers

PMID29340252
PMCPMC5767332
OpenAlexW2783483913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.