ReviewInternational journal of hematology-oncology and stem cell research2017
Mechanism Action of Platelets and Crucial Blood Coagulation Pathways in Hemostasis.
Review in International journal of hematology-oncology and stem cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
164 citing papers in PubMed, 2 syntheses or guidelines pooled it, 351 citations in OpenAlex.
- The Use of Total Thrombus Formation Analysis System as a Tool to Assess Platelet Function in Bleeding and Thrombosis Risk-A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis.Frontiers in neurology · 2020Pooled it
- Electrospun Heparin-Loaded PCL Nanofiber Sutures with Sustained Release for Antithrombotic Applications.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Differences in thromboelastometry parameters A10EXTEM and A10FIBTEM -as independent risk factors for mortality during bleeding.Langenbeck's archives of surgery · 2026Article
- Thrombogenic characterization of alloyed and surface-modified magnesium bioresorbable metals for cardiovascular device applications.Biomaterials · 2026Article
- Fibrin, from blood to bone: a review.Bone reports · 2026Review
- Utility of point-of-care platelet aggregation testing for transfusion prediction.Scientific reports · 2026Article
- Nanofibrous Platforms for Advanced Wound Therapeutics: Mechanisms, Materials, and Clinical Horizons.Macromolecular bioscience · 2026Review
- The impact of rapid infusers on the hemostatic potential of cryoprecipitate products.Transfusion · 2026Article
- Large Animal Models for Preclinical Evaluation of Heart Valve Prostheses, Left Ventricular Assist Devices and Total Artificial Hearts: A Narrative Review.Biomimetics (Basel, Switzerland) · 2026Review
- Redefining Dual Antiplatelet Strategies After Acute Coronary Syndrome: Insights from Recent RCTs.Journal of clinical medicine · 2026Review
- A Neutrophil-like Cell Model as Substitute for Human Neutrophils in NETs and Thrombosis Research.Cells · 2026Article
- Development and validation of a nomogram for predicting thrombocytopenia in sepsis patients treated with linezolid.BMC pharmacology & toxicology · 2026Article
- Exploring the Complexities of Bone Implants and Stents: Factors Influencing Successful Tissue Integration.Advances in experimental medicine and biology · 2026Review
- Preparation and evaluation of a small-diameter vascular graft with dual anticoagulant and anticalcification functions.Regenerative biomaterials · 2026Article
- Standardization of canine platelet-rich plasma preparation and its functional characterization.Journal of veterinary science · 2026Article
- A systematic review of the biological effects of resveratrol on venous thromboembolism.Avicenna journal of phytomedicine · 2026Review
- Recent advances in the treatment of retinal vein occlusion with traditional Chinese medicine.International ophthalmology · 2025Review
- Immunomodulatory bioadhesive technologies.Biomaterials · 2025Review
- A 2D computational model of chemically- and mechanically-induced platelet plug formation.Biomechanics and modeling in mechanobiology · 2025Article
104 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood is considered to be precious because it is the basic necessity for health; our body needs a steady provision of oxygen, supplied via blood, to reach billions of tissues and cells. Hematopoiesis is the process that generates blood cells of all lineages. However, platelets are the smallest blood component produced from the very large bone marrow cells called megakaryocytes and they play a fundamental role in thrombosis and hemostasis. Platelets contribute their hemostatic capacity via adhesion, activation and aggregation, which are triggered upon tissue injury, and these actions stimulate the coagulation factors and other mediators to achieve hemostasis. In addition, these coordinated series of events are the vital biological processes for wound healing phases. The aim of this review is to summarize and highlight the important pathways involved in achieving hemostasis that are ruled by platelets. In addition, this review also describes the mechanism action of platelets, including adhesion, activation, aggregation, and coagulation, as well as the factors that aid in hemostasis and wound healing.
Indexed as
Identifiers
29340130PMC5767294W2771457674What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.