ArticleOncotarget2017
Survival benefit evaluation of radiotherapy in esophageal cancer patients aged 80 and older.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Therapeutic Approaches to Increase the Survival Rate of Cancer Patients in the Younger and Older Population.Current aging science · 2024Review
- Individualized treatment decision model for inoperable elderly esophageal squamous cell carcinoma based on multi-modal data fusion.BMC medical informatics and decision making · 2023Article
- The benefit of concurrent chemotherapy with radiotherapy for esophageal cancer is limited in Asian patients aged 80 years or older: a SEER database analysis.Esophagus : official journal of the Japan Esophageal Society · 2022Article
- Management of elderly patients with esophageal squamous cell cancer.Japanese journal of clinical oncology · 2022Review
- Proton beam therapy is a safe and effective treatment in elderly patients with esophageal squamous cell carcinoma.Thoracic cancer · 2020Article
- Chemoradiotherapy and radiotherapy alone in patients with esophageal cancer aged 80 years or older based on the Comprehensive Registry of Esophageal Cancer in Japan.Esophagus : official journal of the Japan Esophageal Society · 2020Article
- Investigating the Survival Benefit of Combining Radiotherapy for Surgery Treated Locally Advanced Esophageal Squamous Cell Carcinoma Patients Aged 65 and Older.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Definitive Radiotherapy for Older Patients Aged ≥75 Years With Localized Esophageal Cancer.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the survival benefit of radiotherapy (RT) in esophageal cancer (EC) patients aged ≥ 80. MATERIALS AND
methodsRecords for all EC patients aged ≥ 65 years were extracted from the Surveillance, Epidemiology, and End Results database. Chi-square test compared the characteristic and treatment between patients aged ≥ 80 with those aged 65-79. Focusing on patients aged ≥ 80, we employed multivariable logistic regression to identify the association between selection of RT and patients' characteristics. Survival curve was employed to visualize the survival rate and multivariable Cox proportional hazard model was established to quantify the effect of RT on overall survival (OS) and cancer special survival (CSS).
resultsPatients aged ≥ 80 were more likely to be white male and have localized EC (all
conclusionsOur study suggested EC patients aged ≥ 80 benefit from RT only if the cancer is in localized/regional stage.
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Registered trials
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