The effects of tumor necrosis factor-α (TNF-α) rs1800629 and rs361525 polymorphisms on sepsis risk.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

1. Single Nucleotide Polymorphisms and Post-operative Complications Following Major Gastrointestinal Surgery: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
   Pooled it
2. Associations of tumor necrosis factor alpha genetic variants with metabolic syndrome and type 2 diabetes mellitus in a Thai population.PloS one · 2026
   Article
3. Genetic associations in sepsis and ARDS.Frontiers in pharmacology · 2026
   Review
4. Gene expression kinetics in Sepsis After Cardiac Surgery (SACS): a multicentric prospective observational study.Journal of anesthesia, analgesia and critical care · 2025
   Article
5. Genotype-Phenotype Correlation of TNF-α (-238, rs361525) and Cystatin C for Early Detection of Sepsis-Associated AKI and Its Severity in Critically Ill Neonates.International journal of molecular sciences · 2025
   Article
6. Molecular Determination of Tumor Necrosis Factor-alpha, Interleukin-8, Interleukin-10, and C-X-C Chemokine Receptor-2 Genetic Variations and their Association with Disease Susceptibility and Mortality in COVID-19 Patients.Current genomics · 2024
   Article
7. Associations of Tumor Necrosis Factor-Alpha Gene PolymorphismsLife (Basel, Switzerland) · 2022
   Article
8. Association of tumor necrosis factor alpha -308 single nucleotide polymorphism with SARS CoV-2 infection in an Iraqi Kurdish population.Journal of clinical laboratory analysis · 2022
   Article
9. Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.Journal of medical virology · 2022
   Article
10. The Role of Immunogenetics in COVID-19.International journal of molecular sciences · 2021
    Review
11. Potential Value of TNF-α (-376 G/A) Polymorphism and Cystatin C (CysC) in the Diagnosis of Sepsis Associated Acute Kidney Injury (S-AK I) and Prediction of Mortality in Critically Ill patients.Frontiers in molecular biosciences · 2021
    Article
12. Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression.BMC infectious diseases · 2020
    Article
13. Two novel SNPs in genes involved in immune response and their association with mandibular residual ridge resorption.Saudi journal of biological sciences · 2020
    Article
14. Long non-coding RNA-HOTAIR promotes the progression of sepsis by acting as a sponge of miR-211 to induce IL-6R expression.Experimental and therapeutic medicine · 2019
    Article
15. Genetic polymorphisms associated with sepsis incidence, severity, and outcomes among neonates: A mini-review.Journal of advanced pharmaceutical technology & research
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as