Evidence map›Paper›PMID 29339975›Full record

ArticleGenes & nutrition2018

Genetic polymorphisms of antioxidant enzymes CAT and SOD affect the outcome of clinical, biochemical, and anthropometric variables in people with obesity under a dietary intervention.

César Hernández-Guerrero, Alicia Parra-Carriedo, Diana Ruiz-de-Santiago, Oscar Galicia-Castillo, Mario Buenrostro-Jáuregui, Carmen Díaz-Gutiérrez

Open access · goldAbstract read
In one paragraph

Article in Genes & nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antioxidants-Related Superoxide Dismutase (Antioxidants (Basel, Switzerland) · 2021
    Article
  9. Oxidative Stress and Analysis of Selected SNPs ofInternational journal of molecular sciences · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

César Hernández-GuerreroDepartamento de Salud, Universidad Iberoamericana, Prol. Paseo de la Reforma 880, Col Santa Fe, 01219 México City, Mexico.ORCID 0000-0002-1196-5073
Alicia Parra-CarriedoDepartamento de Salud, Universidad Iberoamericana, Prol. Paseo de la Reforma 880, Col Santa Fe, 01219 México City, Mexico.
Diana Ruiz-de-SantiagoEspecialidad en Obesidad y Comorbilidades, Universidad Iberoamericana, Ciudad de México, Mexico.
Oscar Galicia-CastilloDepartamento de Psicología, Universidad Iberoamericana, Ciudad de México, Mexico.
Mario Buenrostro-JáureguiDepartamento de Psicología, Universidad Iberoamericana, Ciudad de México, Mexico.
Carmen Díaz-GutiérrezDepartamento de Salud, Universidad Iberoamericana, Prol. Paseo de la Reforma 880, Col Santa Fe, 01219 México City, Mexico.
Ibero American University · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGenetic polymorphisms of antioxidant enzymes CAT, GPX, and SOD are involved in the etiology of obesity and its principal comorbidities. The aim of the present study was to analyze the effect of aforementioned SNPs over the output of several variables in people with obesity after a nutritional intervention. The study included 92 Mexican women, which received a dietary intervention by 3 months. Participants were genotyped and stratified into two groups: (1) carriers; mutated homozygous plus heterozygous (CR) and (2) homozygous wild type (WT). A comparison between CR and WT was done in clinical (CV), biochemical (BV), and anthropometric variables (AV), at the beginning and at the end of the intervention.

resultsParticipants (

conclusionPeople with obesity display different response in several CV, BV, and AV after a nutritional intervention, depending on the antioxidant genetic background of SOD and CAT enzymes.

Indexed as

CATGenetic polymorphismGPXObesitySOD

Identifiers

PMID29339975
PMCPMC5759352
OpenAlexW2782685447

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.