Evidence map›Paper›PMID 29339838›Full record

ArticleMacromolecules2018

Force and Scale Dependence of the Elasticity of Self-Assembled DNA Bottle Brushes.

Márcio Santos Rocha, Ingeborg M Storm, Raniella Falchetto Bazoni, Ésio Bessa Ramos, Armando Hernandez-Garcia, Martien A Cohen Stuart, Frans Leermakers, Renko de Vries

Erratum issuedAbstract read
In one paragraph

Article in Macromolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Direct-ink-write cross-linkable bottlebrush block copolymers for on-the-fly control of structural color.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Márcio Santos RochaLaboratório de Física Biológica, Departamento de Física, Universidade Federal de Viçosa Viçosa, Minas Gerais, Brazil.
Ingeborg M StormPhysical Chemistry and Soft Matter, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Raniella Falchetto BazoniLaboratório de Física Biológica, Departamento de Física, Universidade Federal de Viçosa Viçosa, Minas Gerais, Brazil.
Ésio Bessa RamosLaboratório de Física Biológica, Departamento de Física, Universidade Federal de Viçosa Viçosa, Minas Gerais, Brazil.
Armando Hernandez-GarciaDepartamento de Química de Biomacromoleculas, Instituto de Química, Universidad Nacional Autónoma de México, México City, México.
Martien A Cohen StuartPhysical Chemistry and Soft Matter, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Frans LeermakersPhysical Chemistry and Soft Matter, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Renko de VriesPhysical Chemistry and Soft Matter, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a model system to study the elasticity of bottle-brush polymers, we here introduce self-assembled DNA bottle brushes, consisting of a DNA main chain that can be very long and still of precisely defined length, and precisely monodisperse polypeptide side chains that are physically bound to the DNA main chains. Polypeptide side chains have a diblock architecture, where one block is a small archaeal nucleoid protein Sso7d that strongly binds to DNA. The other block is a net neutral, hydrophilic random coil polypeptide with a length of exactly 798 amino acids. Light scattering shows that for saturated brushes the grafting density is one side chain per 5.6 nm of DNA main chain. According to small-angle X-ray scattering, the brush diameter is

Identifiers

PMID29339838
PMCPMC5763285

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.