Evidence map›Paper›PMID 29339722›Full record

ArticleNature communications2018

The deep-subsurface sulfate reducer Desulfotomaculum kuznetsovii employs two methanol-degrading pathways.

Diana Z Sousa, Michael Visser, Antonie H van Gelder, Sjef Boeren, Mervin M Pieterse, Martijn W H Pinkse, Peter D E M Verhaert, Carsten Vogt, Steffi Franke, Steffen Kümmel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Cobalt modulates methanol turnover of the alcohol dehydrogenase inApplied and environmental microbiology · 2025
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  19. Patterns ofFrontiers in microbiology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Diana Z SousaLaboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Michael VisserLaboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.ORCID http://orcid.org/0000-0002-2049-9342
Antonie H van GelderLaboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Sjef BoerenLaboratory of Biochemistry, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.ORCID http://orcid.org/0000-0002-0847-8821
Mervin M PieterseDepartment of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands.
Martijn W H PinkseDepartment of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands.
Peter D E M VerhaertDepartment of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands.ORCID http://orcid.org/0000-0002-6921-087X
Carsten VogtDepartment of Isotope Biogeochemistry, UFZ-Helmholtz Centre for Environmental Research, Permoserstraße 15, 04318, Leipzig, Germany.
Steffi FrankeDepartment of Isotope Biogeochemistry, UFZ-Helmholtz Centre for Environmental Research, Permoserstraße 15, 04318, Leipzig, Germany.
Steffen KümmelDepartment of Isotope Biogeochemistry, UFZ-Helmholtz Centre for Environmental Research, Permoserstraße 15, 04318, Leipzig, Germany.
Alfons J M StamsLaboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands. fons.stams@wur.nl.
Wageningen University & Research · NLHelmholtz Centre for Environmental Research · DEJuliana Kinderziekenhuis · NLJanssen (Belgium) · BE

Funding

European Research Council 323009
6 · The paper itself

Abstract

Methanol is generally metabolized through a pathway initiated by a cobalamine-containing methanol methyltransferase by anaerobic methylotrophs (such as methanogens and acetogens), or through oxidation to formaldehyde using a methanol dehydrogenase by aerobes. Methanol is an important substrate in deep-subsurface environments, where thermophilic sulfate-reducing bacteria of the genus Desulfotomaculum have key roles. Here, we study the methanol metabolism of Desulfotomaculum kuznetsovii strain 17

Indexed as

Alcohol DehydrogenaseBacterial ProteinsCobaltCulture MediaDesulfotomaculumGene ExpressionGene Expression ProfilingHydrolysisMetabolic Networks and PathwaysMethanolMethyltransferasesOxidation-ReductionPhylogenyProteomicsVitamin B 12Alcohol DehydrogenaseBacterial ProteinsCobaltcobaltous chlorideCulture MediaMethanolMethyltransferasesVitamin B 12

Identifiers

PMID29339722
PMCPMC5770442
OpenAlexW2783064964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.