Evidence map›Paper›PMID 29339697›Full record

ArticleAnatolian journal of cardiology2018

The value of real-time myocardial contrast echocardiography for detecting coronary microcirculation function in coronary artery disease patients.

Lulu Sun, Zilong Wang, Tongda Xu, Defeng Pan, Li Liang, Ji Hao, Xiaoping Wang, Dongye Li

Abstract readEvaluation Study
In one paragraph

Article in Anatolian journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lulu Sun
Zilong Wang
Tongda Xu
Defeng Pan
Li Liang
Ji Hao
Xiaoping Wang
Dongye LiInstitute of Cardiovascular Disease Research, Xuzhou Medical University, Jiangsu Province-P. R. China. dongyeli@xzhmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the value of real-time myocardial contrast echocardiography (RT-MCE) for detecting coronary microcirculation (CM) function in coronary artery disease (CAD) patients.

methodsSixty-five consecutive patients were divided into CAD (n=52) and no-CAD (n=13) groups using coronary angiography (CAG). All patients underwent RT-MCE at rest and CAG within 1 week after RT-MCE. The ventricular segments in CAD patients were divided semi-quantitatively into ischemic and non-ischemic myocardial groups based on RT-MCE images. Myocardial blood volume (A), myocardial blood flow velocity (ß), and mean myocardial blood flow (Axβ) were obtained. The Gensini scores were calculated for CAD patients. The receiver operating characteristic (ROC) curve areas of A, ß, and Axß were calculated to assess CM function in CAD patients.

resultsA total of 798 and 204 segments were investigated in the CAD and non-CAD groups, respectively. In CAD patients, 332 ischemic and 466 non-ischemic segments were identified. The values of A, ß, and Axß were significantly different among non-CAD, CAD, ischemic, and nonischemic groups. ROC curve areas of A, ß, and Axß were 0.85, 0.79, and 0.83, respectively, and significant differences were observed in these values among three Gensini score groups of the CAD patients.

conclusionVarying degrees of CM function deterioration was observed in CAD patients both in ischemic and non-ischemic areas, with the deterioration being more sever in the former.

Indexed as

Blood Flow VelocityCoronary Artery DiseaseEchocardiographyFemaleHumansMaleMicrocirculationMiddle AgedMyocardiumROC CurveSensitivity and Specificity

Identifiers

PMID29339697
PMCPMC5864787

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