Evidence map›Paper›PMID 29339537›Full record

ArticleCancer research2018

Uksha Saini, Adrian A Suarez, Shan Naidu, John J Wallbillich, Kristin Bixel, Ross A Wanner, Jason Bice, Raleigh D Kladney, Jenny Lester, Beth Y Karlan and 3 more

Abstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Signaling pathways and targeted interventions for precancers.Signal transduction and targeted therapy · 2026
    Review
  4. Article
  5. Article
  6. Roles of STAT3 in the pathogenesis and treatment of glioblastoma.Frontiers in cell and developmental biology · 2023
    Review
  7. Multispectral Staining and Analysis of Extracellular Matrix.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  8. Article
  9. Current and Futuristic Roadmap of Ovarian Cancer Management: An Overview.Advances in experimental medicine and biology · 2021
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Uksha SainiDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Adrian A SuarezDepartment of Pathology, Gynecological Pathology and Cytopathology Unit, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Shan NaiduDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
John J WallbillichDivision of Gynecologic Oncology, Department of OB/GYN, Georgia Cancer Center, Augusta University, Augusta, Georgia.
Kristin BixelDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Ross A WannerDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Jason BicePathology Core Lab, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Raleigh D KladneyPathology Core Lab, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Jenny LesterDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, California.
Beth Y KarlanDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, California.
Paul J GoodfellowDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
David E CohnDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.
Karuppaiyah SelvendiranDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio. selvendiran.karuppaiyah@osumc.edu.
The Ohio State University Wexner Medical Center · USCedars-Sinai Medical Center · USAugusta University Health · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Dissecting the role of STAT3 and targeting ovarian cancerR01CA176078 · NCI · OHIO STATE UNIVERSITY · PI KARUPPAIYAH, SELVENDIRAN · 2014 to 2018
$1.6M
Georgia Regents University Women's Reproductive Health Research Career Development PlanK12HD085817 · NICHD · AUGUSTA UNIVERSITY · PI GHAMANDE, SHARAD A. · 2015 to 2019
$1.4M
NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA176078NICHD NIH HHS K12 HD085817
6 · The paper itself

Abstract

The initial molecular events that lead to malignant transformation of the fimbria of the fallopian tube (FT) through high-grade serous ovarian carcinoma (HGSC) remain poorly understood. In this study, we report that increased expression of signal transducer and activator of transcription 3 (

Indexed as

AnimalsCell Line, TumorCell MovementCell Transformation, NeoplasticCystadenocarcinoma, SerousFallopian Tube NeoplasmsFallopian TubesFemaleHumansMiceMolecular ChaperonesOvarian NeoplasmsPrecancerous ConditionsProtein Inhibitors of Activated STATProto-Oncogene Proteins c-mycSTAT3 Transcription FactorMolecular ChaperonesMYC protein, humanPIAS3 protein, humanProtein Inhibitors of Activated STATProto-Oncogene Proteins c-mycSTAT3 protein, humanSTAT3 Transcription FactorTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID29339537
PMCPMC5907493
OpenAlexW2782627672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.