Evidence map›Paper›PMID 29339494›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Strongly enhanced bacterial bioluminescence with the

Carola Gregor, Klaus C Gwosch, Steffen J Sahl, Stefan W Hell

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 147 citations in OpenAlex.

  1. Article
  2. Review
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  4. AnMicrobiology spectrum · 2026
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  9. TheeLife · 2025
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  11. ThebioRxiv : the preprint server for biology · 2025
    Article
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  16. Article
  17. Characterization ofFrontiers in cellular and infection microbiology · 2024
    Article
  18. Monitoring RVFV Infection Using Bioluminescent Reporter Viruses In Vivo.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  19. Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carola GregorDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany; cgregor@mpibpc.mpg.de shell@mpibpc.mpg.de.
Klaus C GwoschDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Steffen J SahlDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Stefan W HellDepartment of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany; cgregor@mpibpc.mpg.de shell@mpibpc.mpg.de.ORCID 0000-0002-9638-5077
Max Planck Institute for Biophysical Chemistry · DEMax Planck Institute for Medical Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioluminescence imaging of single cells is often complicated by the requirement of exogenous luciferins that can be poorly cell-permeable or produce high background signal. Bacterial bioluminescence is unique in that it uses reduced flavin mononucleotide as a luciferin, which is abundant in all cells, making this system purely genetically encodable by the

Indexed as

Anti-Bacterial AgentsEscherichia coliGenes, BacterialLuciferases, BacterialLuminescent MeasurementsMutagenesis, Site-DirectedOperonPhotorhabdusRecombinant ProteinsSingle-Cell AnalysisAnti-Bacterial AgentsLuciferases, BacterialRecombinant Proteinsantibioticsbacteriabioluminescenceluciferasemicroscopy

Identifiers

PMID29339494
PMCPMC5798359
OpenAlexW2783286406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.