Evidence map›Paper›PMID 29339482›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Global spectral clustering in dynamic networks.

Fuchen Liu, David Choi, Lu Xie, Kathryn Roeder

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. PARROT: Phase-Altering Regulatory Rewiring Over Time.bioRxiv : the preprint server for biology · 2026
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  6. Bias-adjusted spectral clustering in multi-layer stochastic block models.Journal of the American Statistical Association · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fuchen LiuDepartment of Statistics and Data Science, Carnegie Mellon University, Pittsburgh, PA 15213.
David ChoiHeinz College, Carnegie Mellon University, Pittsburgh, PA 15213.
Lu XieDepartment of Statistics and Data Science, Carnegie Mellon University, Pittsburgh, PA 15213.
Kathryn RoederDepartment of Statistics and Data Science, Carnegie Mellon University, Pittsburgh, PA 15213; roeder@andrew.cmu.edu.

Funding

Genetics Association in Schizophrenia and Other DisordersR37MH057881 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEVLIN, BERNIE · 2013 to 2022
$5.4M
2/3 Multidimensional investigation of the etiology of autism spectrum disorderR01MH109900 · NIMH · CARNEGIE-MELLON UNIVERSITY · PI ROEDER, KATHRYN M · 2016 to 2018
$578k
NIMH NIH HHS R01 MH109900NIMH NIH HHS R37 MH057881
6 · The paper itself

Abstract

Community detection is challenging when the network structure is estimated with uncertainty. Dynamic networks present additional challenges but also add information across time periods. We propose a global community detection method, persistent communities by eigenvector smoothing (PisCES), that combines information across a series of networks, longitudinally, to strengthen the inference for each period. Our method is derived from evolutionary spectral clustering and degree correction methods. Data-driven solutions to the problem of tuning parameter selection are provided. In simulations we find that PisCES performs better than competing methods designed for a low signal-to-noise ratio. Recently obtained gene expression data from rhesus monkey brains provide samples from finely partitioned brain regions over a broad time span including pre- and postnatal periods. Of interest is how gene communities develop over space and time; however, once the data are divided into homogeneous spatial and temporal periods, sample sizes are very small, making inference quite challenging. Applying PisCES to medial prefrontal cortex in monkey rhesus brains from near conception to adulthood reveals dense communities that persist, merge, and diverge over time and others that are loosely organized and short lived, illustrating how dynamic community detection can yield interesting insights into processes such as brain development.

Indexed as

Cluster AnalysisGene Regulatory NetworksAlgorithmsAnimalsComputer SimulationGene Expression Regulation, DevelopmentalMacaca mulattaModels, GeneticModels, NeurologicalModels, StatisticalPrefrontal Cortexcommunity detectiondynamic networksgene expression networks

Identifiers

PMID29339482
PMCPMC5798376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.