Evidence map›Paper›PMID 29339423›Full record

ArticlemBio2018

Immune Protection against Lethal Fungal-Bacterial Intra-Abdominal Infections.

Elizabeth A Lilly, Melanie Ikeh, Evelyn E Nash, Paul L Fidel, Mairi C Noverr

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. The role of trained immunity in sepsis.Frontiers in immunology · 2024
    Review
  4. Review
  5. Candida-bacterial cross-kingdom interactions.Trends in microbiology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Efficacy ofFrontiers in cellular and infection microbiology · 2022
    Article
  10. Myeloid-derived suppressor cells and vaccination against pathogens.Frontiers in cellular and infection microbiology · 2022
    Review
  11. Review
  12. COVID-19 in Immunosuppressed Children.Frontiers in pediatrics · 2021
    Review
  13. Metabolic Adaptations DuringFrontiers in immunology · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Applying the Host-Microbe Damage Response Framework toJournal of fungi (Basel, Switzerland) · 2020
    Review
  18. Article
  19. Fungal-Bacterial Interactions in Health and Disease.Pathogens (Basel, Switzerland) · 2019
    Review
  20. Journal of fungi (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elizabeth A LillyCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Centre School of Dentistry, New Orleans, Louisiana, USA.
Melanie IkehCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Centre School of Dentistry, New Orleans, Louisiana, USA.
Evelyn E NashCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Centre School of Dentistry, New Orleans, Louisiana, USA.
Paul L FidelCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Centre School of Dentistry, New Orleans, Louisiana, USA.
Mairi C NoverrCenter of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Centre School of Dentistry, New Orleans, Louisiana, USA mnover@lsuhsc.edu.
Louisiana State University Health Sciences Center New Orleans · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Host and microbial factors promoting synergistic mortality during polymicrobial intra-abdominal infections with Candida albicans and Staphylococcus aureusR01AI116025 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI NOVERR, MAIRI C · 2015 to 2019
$1.8M
NIAID NIH HHS R01 AI116025NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Polymicrobial intra-abdominal infections (IAIs) are clinically prevalent and cause significant morbidity and mortality, especially those involving fungi. Our laboratory developed a mouse model of IAI and demonstrated that intraperitoneal inoculation with

Indexed as

AnimalsCandidiasisCoinfectionDisease Models, AnimalIntraabdominal InfectionsMiceNeutrophilsStaphylococcal InfectionsSurvival AnalysisCandida albicansimmune protectioninnate immunityintra-abdominal infectionStaphylococcus aureus

Identifiers

PMID29339423
PMCPMC5770546
OpenAlexW2782864181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.