Evidence map›Paper›PMID 29339407›Full record

ArticleG3 (Bethesda, Md.)2018

Genomic Identification and Functional Characterization of Essential Genes in

Zhaozhao Qin, Robert Johnsen, Shicheng Yu, Jeffrey Shih-Chieh Chu, David L Baillie, Nansheng Chen

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  7. Article
  8. Article
  9. Frontiers in endocrinology · 2020
    Review
  10. Predicting gene essentiality inComputational and structural biotechnology journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhaozhao QinDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Robert JohnsenDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Shicheng YuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Wuhan University, 430071, China.
Jeffrey Shih-Chieh ChuWuhan Frasergen Bioinformatics, Wuhan East Lake High-Tech Zone, 430075, China.
David L BaillieDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Nansheng ChenDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada chenn@sfu.ca.
Simon Fraser University · CAWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using combined genetic mapping, Illumina sequencing, bioinformatics analyses, and experimental validation, we identified 60 essential genes from 104 lethal mutations in two genomic regions of

Indexed as

Genes, EssentialGenetic Association StudiesGenome, HelminthGenomicsAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChromosome MappingComputational BiologyGene OntologyMolecular Sequence AnnotationMutationPolymorphism, Single NucleotideReproducibility of ResultsWhole Genome SequencingCaenorhabditis elegans Proteinsessential genefunctional characterizationgenetic balancerlethalwhole genome sequencing (WGS)

Identifiers

PMID29339407
PMCPMC5844317
OpenAlexW2600401996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.