Observational studyCritical care (London, England)2018
Incidence, risk factors and impact of protocolised care on exposure keratopathy in critically ill adults: a two-phase prospective cohort study.
Observational study in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Ocular Surface Disorders in ICU Patients: Evidence-Based Nursing Prevention Strategies.Translational vision science & technology · 2025Pooled it
- The effect of polyethylene cover intervention on ocular surface disorder of intensive care unit patients: a systematic review and meta-analysis.BMC ophthalmology · 2024Pooled it
- Prevalence and risk factors of exposure keratopathy among critically ill patients: A systematic review and meta-analysis.Nursing open · 2024Pooled it
- Effect of Polyethylene Cover for Preventing Corneal Injury in Critically Ill Patients: A Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- The effect of eye care protocol on the prevention of ocular surface disorders in patients admitted to intensive care unit.Journal of medicine and life · 2022Trial
- Corneal abrasions in burn admissions: severity and geographic access factors in a retrospective cohort.Proceedings (Baylor University. Medical Center) · 2026Article
- Ocular diseases and their association with mortality in intensive care unit patients: a retrospective cohort study from the MIMIC-IV database.BMJ open ophthalmology · 2026Article
- Article
- ICU-Associated Exposure Keratopathy and Preventable Corneal Blindness: A Clinical Review.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Construction and application of an eye care plan for ICU patients receiving prone position ventilation: a quasi-experimental study.Frontiers in health services · 2026Article
- Lens on eye care in intensive care units: deficiencies, training, and improvement recommendations - a descriptive observational study.BMC nursing · 2025Article
- Knowledge, Attitudes and Practices of Critical Care Nurses Regarding Eye Care Across 17 Hospitals: A Multicentre Cross-Sectional Survey.Nursing in critical care · 2025Article
- [Treatment algorithm: eye care for critically ill patients].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023Article
- Impact of ocular care training of nursing staff on the incidence of ocular surface disorder in medical intensive care unit patients.Indian journal of ophthalmology · 2023Article
- Prevention of exposure keratitis in Ontario intensive care units: a survey study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Risk Factors of Eye Complications in Patients Treated in the Intensive Care Unit.International journal of environmental research and public health · 2021Article
- Optimising COVID-19 survivorship after ICU - Don't forget eye care.Intensive & critical care nursing · 2021Article
- Incidence and related factors of surface eye disorders in traumatic intensive care unit patients in Iran.International journal of burns and trauma · 2021Article
- The Effects of Passive Blinking on Exposure Keratopathy among Patients in Intensive Care Units.Iranian journal of nursing and midwifery researchArticle
- Periorbital lesions in severely burned patients.Romanian journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure keratopathy (EK) has a high incidence in critically ill patients. We aimed to determine the rate of EK in patients admitted to our intensive care unit (ICU), identify risk factors for developing EK and ascertain the effectiveness of a protocol to prevent EK.
methodsWe undertook a two-phase prospective cohort single-centre study in a general adult ICU. The first phase of the study was observational. In the second phase of the study an eye care protocol was introduced. Daily ophthalmic assessment was carried out using a portable slit lamp. We also recorded Acute Physiology and Chronic Health Evaluation II score, daily Sequential Organ Failure Assessment score, mechanical ventilation, Richmond Agitation-Sedation Scale, and level of eye care. Student's t test and χ
resultsWe studied 371 patients. In the first phase, the overall rate of EK was 21% but the rate in mechanically ventilated patients was 56%; χ
conclusionsEK is common in critically ill patients, and is associated with mechanical ventilation and incomplete eye closure. A simple protocol substantially reduces the incidence of EK and is easily achieved in clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.