ArticleVirology journal2018
Transcriptome profiling of whitefly guts in response to Tomato yellow leaf curl virus infection.
Article in Virology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- ATP-dependent binding cassette transporter ClABCI6 promotes the expression of citrus yellow vein clearing virus via inhibiting salicylic acid pathway.Journal of plant research · 2026Article
- Gene expression differences in Bemisia tabaci following acquisition of an Old World begomovirus.Scientific data · 2025Article
- Multi-omics analysis reveals discordant proteome and transcriptome responses in larval guts of Frankliniella occidentalis infected with an orthotospovirus.Insect molecular biology · 2025Article
- Review
- Bioactive Phyto-Compounds with Antimicrobial Effects and AI: Results of a Desk Research Study.Microorganisms · 2024Review
- Comparative transcriptome analysis of whiteflies raised onFrontiers in veterinary science · 2024Article
- Potato psyllids mount distinct gut responses against two different 'Candidatus Liberibacter solanacearum' haplotypes.PloS one · 2023Article
- A balance between vector survival and virus transmission is achieved through JAK/STAT signaling inhibition by a plant virus.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- A Review on Transcriptional Responses of Interactions between Insect Vectors and Plant Viruses.Cells · 2022Review
- Comparative transcriptome profiling reveals a network of differentially expressed genes in Asia II 7 and MEAM1 whitefly cryptic species in response to early infection ofFrontiers in microbiology · 2022Article
- Article
- Review
- Article
- A vector whitefly endocytic receptor facilitates the entry of begomoviruses into its midgut cells via binding to virion capsid proteins.PLoS pathogens · 2020Article
- Deep Sequencing of Small RNAs in the WhiteflyInsects · 2020Article
- Transcriptome Analysis of Gene Expression Profiles ofInsects · 2020Article
- Transcriptome analysis and comparison reveal divergence between the Mediterranean and the greenhouse whiteflies.PloS one · 2020Article
- Article
- Comparative proteomic analysis provides new insight into differential transmission of two begomoviruses by a whitefly.Virology journal · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant viruses in agricultural crops are of great concern worldwide, and over 75% of them are transmitted from infected to healthy plants by insect vectors. Tomato yellow leaf curl virus (TYLCV) is a begomovirus, which is the largest and most economically important group of plant viruses, transmitted by the whitefly Bemisia tabaci. The circulation of TYLCV in the insect involves complex insect-virus interactions, whereas the molecular mechanisms of these interactions remain ambiguous. The insect gut as a barrier for viral entry and dissemination is thought to regulate the vector specificity. However, due to its tiny size, information for the responses of whitefly gut to virus infection is limited.
methodsWe investigated the transcriptional response of the gut of B. tabaci Middle East-Asia Minor 1 species to TYLCV infection using Illumina sequencing.
resultsA total of 5207 differentially expressed genes (DEGs) between viruliferous and non-viruliferous whitefly guts were identified. Enrichment analyses showed that cargo receptor and ATP-binding cassette (ABC) transporters were enriched in DEGs, and might help the virus to cross gut barrier. TYLCV could perturb cell cycle and DNA repair as a possible result of its replication in the whitefly. Our data also demonstrated that TYLCV can activate whitefly defense responses, such as antimicrobial peptides. Meanwhile, a number of genes involved in intracellular signaling were activated by TYLCV infection.
conclusionsOur results reveal the complex insect-virus relationship in whitefly gut and provide substantial molecular information for the role of insect midguts in virus transmission.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.