ArticleVirulence2018
Whole-Genome-Sequencing characterization of bloodstream infection-causing hypervirulent Klebsiella pneumoniae of capsular serotype K2 and ST374.
Article in Virulence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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Who cites it
34 citing papers in PubMed, 55 citations in OpenAlex.
- Genomic, virulent and phenotypic characterization of a cerebrospinal fluid-derived ST86-KL2 hypervirulent Klebsiella pneumoniae isolate from a patient with meningitis and diabetes mellitus.BMC microbiology · 2026Article
- Comparative genomic and phenotypic analysis of Escherichia coli ST1193 and ST131 from urinary and bloodstream infections: insights into resistance, virulence, and divergent strategies.BMC infectious diseases · 2025Article
- Genomic insights into novel ST7947 carbapenem-resistant hypervirulent Klebsiella pneumoniae: a threat from an Indian hospital setting.Annals of clinical microbiology and antimicrobials · 2025Article
- Review
- Genomic evolution and dissemination of non-conjugative virulence plasmid of ST65 carbapenem-resistant and hypervirulentFrontiers in cellular and infection microbiology · 2025Article
- RES-Xre toxin-antitoxin locusEmerging microbes & infections · 2024Article
- Hypervirulent Capsular Serotypes K1 and K2International journal of molecular sciences · 2024Article
- Characterization and functionality ofFrontiers in cellular and infection microbiology · 2024Article
- Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395Microorganisms · 2023Article
- Multidrug-resistant CTX-M-15-positiveFrontiers in veterinary science · 2023Article
- Comparative Analysis of Diverse Acetyltransferase-Type Toxin-Antitoxin Loci in Klebsiella pneumoniae.Microbiology spectrum · 2022Article
- Transmission of Nonconjugative Virulence or Resistance Plasmids Mediated by a Self-Transferable IncN3 Plasmid from Carbapenem-Resistant Klebsiella pneumoniae.Microbiology spectrum · 2022Article
- Genomic and Immunological Characterization of Hypermucoviscous Carbapenem-ResistantInternational journal of molecular sciences · 2022Article
- Successful treatment of acute respiratory distress syndrome caused by hypervirulentFrontiers in medicine · 2022Article
- Genetic characterization and passage instability of a novel hybrid virulence plasmid in a ST23 hypervirulentFrontiers in cellular and infection microbiology · 2022Article
- Virulence Genotype and Correlation of Clinical Severeness with Presence of the Type VI Secretion System inInfection and drug resistance · 2022Article
- Whole genome sequencing of OXA-232-producingFrontiers in cellular and infection microbiology · 2022Article
- Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniae.Genome medicine · 2021Article
- Neonatal Sepsis: The Impact of Carbapenem-Resistant and HypervirulentFrontiers in medicine · 2021Review
- Transmission Dynamics of Carbapenem-ResistantFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypervirulent K. pneumoniae variants (hvKP) have been increasingly reported worldwide, causing metastasis of severe infections such as liver abscesses and bacteremia. The capsular serotype K2 hvKP strains show diverse multi-locus sequence types (MLSTs), but with limited genetics and virulence information. In this study, we report a hypermucoviscous K. pneumoniae strain, RJF293, isolated from a human bloodstream sample in a Chinese hospital. It caused a metastatic infection and fatal septic shock in a critical patient. The microbiological features and genetic background were investigated with multiple approaches. The Strain RJF293 was determined to be multilocis sequence type (ST) 374 and serotype K2, displayed a median lethal dose (LD50) of 1.5 × 10
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