Evidence map›Paper›PMID 29338060›Full record

ArticlePloS one2018

Biofeedback effect of hybrid assistive limb in stroke rehabilitation: A proof of concept study using functional near infrared spectroscopy.

Kazuya Saita, Takashi Morishita, Hisatomi Arima, Koichi Hyakutake, Toshiyasu Ogata, Kenji Yagi, Etsuji Shiota, Tooru Inoue

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kazuya SaitaDepartment of Neurosurgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Takashi MorishitaDepartment of Neurosurgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Hisatomi ArimaDepartment of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Koichi HyakutakeDepartment of Neurosurgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Toshiyasu OgataDepartment of Neurology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Kenji YagiDepartment of Neurosurgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Etsuji ShiotaDepartment of Rehabilitation Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Tooru InoueDepartment of Neurosurgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Fukuoka University · JPFukuoka University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRobot-assisted rehabilitation has been increasingly drawing attention in the field of neurorehabilitation. The hybrid assistive limb (HAL) is an exoskeleton robot developed based on the "interactive biofeedback" theory, and several studies have shown its efficacy for patients with stroke. We aimed to investigate the mechanisms of the facilitative effect of neurorehabilitation using a single-joint HAL (HAL-SJ) and functional near-infrared spectroscopy (fNIRS). MATERIALS AND

methodsSubacute stroke patients admitted to our hospital were assessed in this study for HAL eligibility. We evaluated motor-related cortical activity using an fNIRS system at baseline and immediately after HAL-SJ treatment on the same day. Cortical activity was determined through the relative changes in the hemoglobin concentrations. For statistical analysis, we compared the number of flexion/extension movements before and immediately after HAL-SJ treatment using paired t-test. fNIRS used both the methods of statistical parametric mapping and random effect analysis.

resultsWe finally included 10 patients (eight men, two women; mean age: 66.8 ± 12.0 years). The mean number of flexion/extension movements within 15 s increased significantly from 4.2 ± 3.1 to 5.3 ± 4.1 immediately after training. fNIRS showed increased cortical activation in the primary motor cortex of the ipsilesional hemisphere immediately after HAL-SJ treatment compared to the baseline condition.

conclusionsThis study is the first to support the concept of the biofeedback effect from the perspective of changes in cortical activity measured with an fNIRS system. The biofeedback effect of HAL immediately increased the task-related cortical activity, and this may address the functional recovery. Further studies are warranted to support our findings.

Indexed as

Exoskeleton DeviceSpectroscopy, Near-InfraredBiofeedback, PsychologyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedStroke RehabilitationTomography, X-Ray Computed

Identifiers

PMID29338060
PMCPMC5770063
OpenAlexW2782569589

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.