Evidence map›Paper›PMID 29338049›Full record

ArticlePloS one2018

Contribution of the ankle-brachial index to improve the prediction of coronary risk: The ARTPER cohort.

Rosa Forés, Maria Teresa Alzamora, Guillem Pera, José Miguel Baena-Díez, Xavier Mundet-Tuduri, Pere Torán

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Vascular ageing: moving from bench towards bedside.European journal of preventive cardiology · 2023
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Rosa ForésCentre d'Atenció Primària Riu Nord- Riu Sud Santa Coloma de Gramenet, Direcció d'Atenció Primària Barcelonés Nord i Maresme, Institut Català de la Salut, Barcelona, Spain.ORCID 0000-0001-7803-7442
Maria Teresa AlzamoraCentre d'Atenció Primària Riu Nord- Riu Sud Santa Coloma de Gramenet, Direcció d'Atenció Primària Barcelonés Nord i Maresme, Institut Català de la Salut, Barcelona, Spain.
Guillem PeraUnitat de Suport a la Recerca Metropolitana Nord, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Mataró, Spain.
José Miguel Baena-DíezCentre d'Atenció Primària La Marina, Direcció d'Atenció Primària Barcelona Ciutat, Institut Català de la Salut, Barcelona, Spain.
Xavier Mundet-TuduriDepartament de Medicina. Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Pere ToránUnitat de Suport a la Recerca Metropolitana Nord, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Mataró, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe different cardiovascular risk prediction scales currently available are not sufficiently sensitive.

aimThe aim of the present study was to analyze the contribution of the ankle-brachial index (ABI) added to the Framingham and REGICOR risk scales for the reclassification of cardiovascular risk after a 9-year follow up of a Mediterranean population with low cardiovascular risk. DESIGN AND

settingA population-based prospective cohort study was performed in the province of Barcelona, Spain.

methodA total of 3,786 subjects >49 years were recruited from 2006-2008. Baseline ABI was performed and cardiovascular risk was calculated with the Framingham and REGICOR scales. The participants were followed until November 2016 by telephone and review of the clinical history every 6 months to confirm the possible appearance of cardiovascular events.

results2,716 individuals participated in the study. There were 126 incidental cases of first coronary events (5%) during follow up. The incidence of coronary events in patients with ABI <0.9 was 4-fold greater than that of subjects with a normal ABI (17.2/1,000 persons-year versus 4.8/1,000 persons-year). Improvement in the predictive capacity of REGICOR scale was observed on including ABI in the model, obtaining a net reclassification improvement of 7% (95% confidence interval 0%-13%) for REGICOR+ ABI. Framingham + ABI obtained a NRI of 4% (-2%-11%).

conclusionThe results of the present study support the addition of the ABI as a tool to help in the reclassification of cardiovascular risk and to confirm the greater incidence of coronary events in patients with ABI < 0.9.

Indexed as

Ankle Brachial IndexAgedCardiovascular DiseasesCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedRisk Factors

Identifiers

PMID29338049
PMCPMC5770061

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.