Evidence map›Paper›PMID 29338029›Full record

ArticlePloS one2018

Implicit learning deficit in children with Duchenne muscular dystrophy: Evidence for a cerebellar cognitive impairment?

Stefano Vicari, Giorgia Piccini, Eugenio Mercuri, Roberta Battini, Daniela Chieffo, Sara Bulgheroni, Chiara Pecini, Simona Lucibello, Sara Lenzi, Federica Moriconi and 7 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  7. Language and the Cerebellum: Structural Connectivity to the Eloquent Brain.Neurobiology of language (Cambridge, Mass.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Stefano VicariDepartment of Neuroscience, Child Neuropsychiatric Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Giorgia PicciniDepartment of Neuroscience, Child Neuropsychiatric Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Eugenio MercuriPediatric Neurology Unit, Catholic University and Nemo Center, Rome, Italy.
Roberta BattiniDepartment of Developmental Neuroscience, IRCCS Stella Maris, Calambrone (Pisa), Italy.
Daniela ChieffoPediatric Neurology Unit, Catholic University and Nemo Center, Rome, Italy.
Sara BulgheroniDevelopmental Neurology Division, IRCCS Fondazione Istituto Neurologico C. Besta, Milan, Italy.
Chiara PeciniDepartment of Developmental Neuroscience, IRCCS Stella Maris, Calambrone (Pisa), Italy.
Simona LucibelloPediatric Neurology Unit, Catholic University and Nemo Center, Rome, Italy.
Sara LenziDepartment of Developmental Neuroscience, IRCCS Stella Maris, Calambrone (Pisa), Italy.
Federica MoriconiPediatric Neurology Unit, Catholic University and Nemo Center, Rome, Italy.
Marika PanePediatric Neurology Unit, Catholic University and Nemo Center, Rome, Italy.
Adele D'AmicoDepartment of Neurosciences, Neuromuscular and Neurodegenerative Diseases Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Guja AstreaDepartment of Developmental Neuroscience, IRCCS Stella Maris, Calambrone (Pisa), Italy.
Giovanni BaranelloDevelopmental Neurology Division, IRCCS Fondazione Istituto Neurologico C. Besta, Milan, Italy.
Daria RivaDevelopmental Neurology Division, IRCCS Fondazione Istituto Neurologico C. Besta, Milan, Italy.
Giovanni CioniDepartment of Developmental Neuroscience, IRCCS Stella Maris, Calambrone (Pisa), Italy.
Paolo AlfieriDepartment of Neuroscience, Child Neuropsychiatric Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Centro Clinico Nemo · ITBambino Gesù Children's Hospital · ITFondazione Stella Maris · ITFondazione IRCCS Istituto Neurologico Carlo Besta · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed at comparing implicit sequence learning in individuals affected by Duchenne Muscular Dystrophy without intellectual disability and age-matched typically developing children. A modified version of the Serial Reaction Time task was administered to 32 Duchenne children and 37 controls of comparable chronological age. The Duchenne group showed a reduced rate of implicit learning even if in the absence of global intellectual disability. This finding provides further evidence of the involvement of specific aspects of cognitive function in Duchenne muscular dystrophy and on its possible neurobiological substrate.

Indexed as

Case-Control StudiesCerebellumChildCognitive DysfunctionHumansLearningLearning DisabilitiesLogistic ModelsMaleMuscular Dystrophy, DuchenneReaction Time

Identifiers

PMID29338029
PMCPMC5770044
OpenAlexW2783584419

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.