ArticleAdvances in neonatal care : official journal of the National Association of Neonatal Nurses2018
Associations Between Nurse-Guided Variables and Plasma Oxytocin Trajectories in Premature Infants During Initial Hospitalization.
Article in Advances in neonatal care : official journal of the National Association of Neonatal Nurses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 17 citations in OpenAlex.
- Application of a Risk Management Framework to Parent Sleep During Skin-to-Skin Care in the NICU.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2022Article
- Changes in Clinical Care of the Newborn During COVID-19 Pandemic: From the Womb to First Newborn Visit.Pediatric clinics of North America · 2021Review
- Reducing toxic stress in the neonatal intensive care unit to improve infant outcomes.Nursing outlookArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundOxytocin (OT) is a social hormone that may help researchers understand how nurse-guided interventions during initial infant hospitalization, such as supporting human milk expression, promoting comforting touch, and reducing exposure to stressors, affect preterm brain development. PURPOSE: To determine whether factors related to human milk, touch, or stressor exposure are related to plasma OT trajectories in premature infants.
methodsPlasma from 33 premature infants, born gestational ages 25 to (Equation is included in full-text article.)weeks, was collected at 14 days of life and then weekly until 34 weeks' corrected gestational age (CGA). Variables related to feeding volumes of human milk and formula; touch, as indexed by skin-to-skin contact (SSC) and swaddled holding; and clinical stressors were extracted from the electronic medical record. Linear mixed-models tested associations between nurse-guided variables and plasma OT trajectories.
resultsIn the final model, same-day SSC was positively related not only to plasma OT levels at 27 weeks' CGA (β= .938, P = .002) but also to a decline in plasma OT levels over time (β=-.177, P = .001). Volume of enteral feeds (mL/kg/d), its interaction with CGA, and number of stressful procedures were not statistically significant (β= .011, P = .077; β=-.002, P = .066; and β= .007, P = .062, respectively). IMPLICATIONS FOR PRACTICE: Nurse-guided interventions are associated with infant plasma OT levels, suggesting nurses may impact the neurobiology of the developing premature infant. IMPLICATIONS FOR RESEARCH: Replication with larger sample sizes and randomized controlled trial designs is needed to test effects of specific nursing interventions on infant OT.
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