ArticleNeuroImage2018
Suprathreshold fiber cluster statistics: Leveraging white matter geometry to enhance tractography statistical analysis.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Study of sex differences in the whole brain white matter using diffusion MRI tractography and suprathreshold fiber cluster statistics.NeuroImage. Clinical · 2026Article
- A Multimodal Deep Learning Approach for White Matter Shape Prediction in Diffusion MRI Tractography.Human brain mapping · 2025Article
- Study of Sex Differences in the Whole Brain White Matter Using Diffusion MRI Tractography and Suprathreshold Fiber Cluster Statistics.bioRxiv : the preprint server for biology · 2025Article
- The Shape of the Brain's Connections Is Predictive of Cognitive Performance: An Explainable Machine Learning Study.Human brain mapping · 2025Review
- Deep fiber clustering: Anatomically informed fiber clustering with self-supervised deep learning for fast and effective tractography parcellation.NeuroImage · 2023Article
- Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review.NeuroImage · 2022Review
- The Organization of Frontostriatal Brain Wiring in Healthy Subjects Using a Novel Diffusion Imaging Fiber Cluster Analysis.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- TRAKO: Efficient Transmission of Tractography Data for Visualization.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020Article
- Deep white matter analysis (DeepWMA): Fast and consistent tractography segmentation.Medical image analysis · 2020Article
- Tractostorm: The what, why, and how of tractography dissection reproducibility.Human brain mapping · 2020Review
- Article
- Test-retest reproducibility of white matter parcellation using diffusion MRI tractography fiber clustering.Human brain mapping · 2019Article
- Article
- An anatomically curated fiber clustering white matter atlas for consistent white matter tract parcellation across the lifespan.NeuroImage · 2018Article
- RapidParc: A global-context transformer for parallel, accurate, and lesion-robust tractogram parcellation.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
This work presents a suprathreshold fiber cluster (STFC) method that leverages the whole brain fiber geometry to enhance statistical group difference analyses. The proposed method consists of 1) a well-established study-specific data-driven tractography parcellation to obtain white matter tract parcels and 2) a newly proposed nonparametric, permutation-test-based STFC method to identify significant differences between study populations. The basic idea of our method is that a white matter parcel's neighborhood (nearby parcels with similar white matter anatomy) can support the parcel's statistical significance when correcting for multiple comparisons. We propose an adaptive parcel neighborhood strategy to allow suprathreshold fiber cluster formation that is robust to anatomically varying inter-parcel distances. The method is demonstrated by application to a multi-shell diffusion MRI dataset from 59 individuals, including 30 attention deficit hyperactivity disorder patients and 29 healthy controls. Evaluations are conducted using both synthetic and in-vivo data. The results indicate that the STFC method gives greater sensitivity in finding group differences in white matter tract parcels compared to several traditional multiple comparison correction methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.