ArticleNeuroImage2018
Validation of diffusion MRI estimates of compartment size and volume fraction in a biomimetic brain phantom using a human MRI scanner with 300 mT/m maximum gradient strength.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- Article
- Axon Diameter Mapping in the Living Human Brain with Ultra-High-Gradient Diffusion MRI at 500 mT/m Gradient Strength.Human brain mapping · 2026Article
- A phantom mimicking layered biological microenvironments investigated with 7T diffusion weighted MRI.Scientific reports · 2026Article
- Distinct cellular processes drive motor skill learning in the human brain.bioRxiv : the preprint server for biology · 2025Article
- In vivo cortical microstructure mapping using high-gradient diffusion MRI accounting for intercompartmental water exchange effects.NeuroImage · 2025Article
- Direct jet coaxial electrospinning of axon-mimicking fibers for diffusion tensor imaging.Polymers for advanced technologies · 2023Article
- Integrating multimodality magnetic resonance imaging to the Allen Mouse Brain Common Coordinate Framework.NMR in biomedicine · 2023Article
- Linear multi-scale modeling of diffusion MRI data: A framework for characterization of oriented structures across length scales.Human brain mapping · 2023Article
- Long-Term Effects of Repeated Blast Exposure in United States Special Operations Forces Personnel: A Pilot Study Protocol.Journal of neurotrauma · 2022Article
- Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact.NeuroImage · 2022Review
- Comprehensive diffusion MRI dataset for in vivo human brain microstructure mapping using 300 mT/m gradients.Scientific data · 2022Article
- Advanced spinal cord MRI in multiple sclerosis: Current techniques and future directions.NeuroImage. Clinical · 2022Review
- Design and characterization of a 3D-printed axon-mimetic phantom for diffusion MRI.Magnetic resonance in medicine · 2021Article
- Review
- Validating pore size estimates in a complex microfiber environment on a human MRI system.Magnetic resonance in medicine · 2021Article
- MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond.European radiology experimental · 2021Review
- Axon diameter index estimation independent of fiber orientation distribution using high-gradient diffusion MRI.NeuroImage · 2020Article
- A validation framework for neuroimaging software: The case of population receptive fields.PLoS computational biology · 2020Article
- High-gradient diffusion MRI reveals distinct estimates of axon diameter index within different white matter tracts in the in vivo human brain.Brain structure & function · 2020Article
- Optimizing Diffusion Imaging Protocols for Structural Connectomics in Mouse Models of Neurological Conditions.Frontiers in physics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Diffusion microstructural imaging techniques have attracted great interest in the last decade due to their ability to quantify axon diameter and volume fraction in healthy and diseased human white matter. The estimates of compartment size and volume fraction continue to be debated, in part due to the lack of a gold standard for validation and quality control. In this work, we validate diffusion MRI estimates of compartment size and volume fraction using a novel textile axon ("taxon") phantom constructed from hollow polypropylene yarns with distinct intra- and extra-taxonal compartments to mimic white matter in the brain. We acquired a comprehensive set of diffusion MRI measurements in the phantom using multiple gradient directions, diffusion times and gradient strengths on a human MRI scanner equipped with maximum gradient strength (G
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.