SynthesisThe British journal of dermatology2018
Systematic review of atopic dermatitis disease definition in studies using routinely collected health data.
Synthesis in The British journal of dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- 12-month prevalence of atopic dermatitis in resource-rich countries: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- What are the highest yielding search strategy terms for systematic reviews in atopic dermatitis? A systematic review.Archives of dermatological research · 2021Pooled it
- Apple cider vinegar soaks do not alter the skin bacterial microbiome in atopic dermatitis.PloS one · 2021Trial
- Development of phenotype algorithms for the detection of adverse events in electronic health record data: a multicentre study.BMJ open · 2026Article
- Association between atopic dermatitis and febrile seizure in young children.BMC pediatrics · 2026Article
- Global trends and modifiable risk factors for atopic dermatitis incidence: Insights from GBD 2021.The journal of allergy and clinical immunology. Global · 2025Article
- From allergens to epigenetics: how histone acetylation shapes immune gene expression in allergic diseases.Epigenomics · 2025Review
- Harmonizing epidemiological research methodology for atopic dermatitis research: protocol for the EPISTAR international consensus exercise.Skin health and disease · 2025Article
- Methods for identifying health status from routinely collected health data: An overview.Integrative medicine research · 2025Article
- Disagreement concerning atopic dermatitis subtypes between an English prospective cohort (ALSPAC) and linked electronic health records.Clinical and experimental dermatology · 2024Article
- Effect of Staphylococcus aureus colonization and immune defects on the pathogenesis of atopic dermatitis.Archives of microbiology · 2024Review
- Antioxidant Activity and the Therapeutic Effect of Sinomenine Hydrochloride-Loaded Liposomes-in-Hydrogel on Atopic Dermatitis.International journal of molecular sciences · 2024Article
- Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Review
- Trends of Diagnosis, Disease Course, and Treatment of Atopic Dermatitis 2012-2021: Real-World Data from a Large Healthcare Provider.Journal of clinical medicine · 2024Article
- Validation of Diagnoses of Atopic Dermatitis in Hospital Registries: A Cross-sectional Database Study from Finland.Acta dermato-venereologica · 2023Article
- Diseases from the Spectrum of Dermatitis and Eczema: Can "Omics" Sciences Help with Better Systematics and More Accurate Differential Diagnosis?International journal of molecular sciences · 2023Review
- Increased risk of osteoarthritis in patients with atopic disease.Annals of the rheumatic diseases · 2023Article
- Validation of medical service insurance claims as a surrogate for ascertaining vitiligo cases.Archives of dermatological research · 2023Article
- The immunological and structural epidermal barrier dysfunction and skin microbiome in atopic dermatitis-an update.Frontiers in molecular biosciences · 2023Review
- Children atopic dermatitis: Diagnosis, mimics, overlaps, and therapeutic implication.Dermatologic therapy · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 3 countries.
Funding
Abstract
backgroundRoutinely collected electronic health data obtained for administrative and clinical purposes are increasingly used to study atopic dermatitis (AD). Methods for identifying AD patients in routinely collected electronic health data differ, and it is unknown how this might affect study results.
objectivesTo evaluate how patients with AD have been identified in studies using routinely collected electronic health data, to determine whether these methods were validated and to estimate how the method for identifying patients with AD affected variability in prevalence estimates.
methodsWe systematically searched PubMed, Embase and Web of Science for studies using routinely collected electronic health data that reported on AD as a primary outcome. Studies of localized AD and other types of dermatitis were excluded. The protocol for this review was registered in PROSPERO (CRD42016037968).
resultsIn total, 59 studies met eligibility criteria. Medical diagnosis codes for inclusion and exclusion, number of occasions of a code, type of provider associated with a code and prescription data were used to identify patients with AD. Only two studies described validation of their methods and no study reported on disease severity. Prevalence estimates ranged from 0·18% to 38·33% (median 4·91%) and up to threefold variation in prevalence was introduced by differences in the method for identifying patients with AD.
conclusionsThis systematic review highlights the need for clear reporting of methods for identifying patients with AD in routinely collected electronic health data to allow for meaningful interpretation and comparison of results.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.