Evidence map›Paper›PMID 29335928›Full record

ArticleInsights into imaging2018

CT imaging of primary pancreatic lymphoma: experience from three referral centres for pancreatic diseases.

Enrico Boninsegna, Giulia A Zamboni, Davide Facchinelli, Charikleia Triantopoulou, Sofia Gourtsoyianni, Maria Chiara Ambrosetti, Dino Veneri, Achille Ambrosetti, Roberto Pozzi Mucelli

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Imaging of non-ductal pancreatic neoplasms.Abdominal radiology (New York) · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Differential Diagnosis of Pancreatic Cancer and its Mimicking Lesions.Journal of the Korean Society of Radiology · 2024
    Review
  7. Article
  8. Article
  9. Frontiers in medicine · 2024
    Article
  10. Rare Solid Pancreatic Lesions on Cross-Sectional Imaging.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Enrico BoninsegnaDepartment of Radiology, Policlinico G. B. Rossi, University of Verona, Verona, Italy. boninsegnae@gmail.com.
Giulia A ZamboniDepartment of Radiology, Policlinico G. B. Rossi, University of Verona, Verona, Italy.
Davide FacchinelliDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.
Charikleia TriantopoulouDepartment of Radiology, Konstantopouleio General Hospital, Athens, Greece.
Sofia GourtsoyianniDepartment of Radiology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Maria Chiara AmbrosettiDepartment of Radiology, Policlinico G. B. Rossi, University of Verona, Verona, Italy.
Dino VeneriDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.
Achille AmbrosettiDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.
Roberto Pozzi MucelliDepartment of Radiology, Policlinico G. B. Rossi, University of Verona, Verona, Italy.
University of Verona · ITAgia Olga Hospital · GRGuy's and St Thomas' NHS Foundation Trust · GB

Funding

European Society of Radiology (ESR) RA-ESR-INII-1116
6 · The paper itself

Abstract

purposeTo describe CT characteristics of primary pancreatic lymphoma (PPL), a rare disease with features in common with adenocarcinoma. MATERIALS AND

methodsFourteen patients were enrolled. CT: unenhanced scan, contrast-enhanced pancreatic and venous phases. Image analysis: tumour location; peri-pancreatic vessel encasement; necrosis; enlarged lymph nodes; fat stranding; enlarged bile duct and pancreatic duct; neoplasm longest dimension, volume and density.

resultsHistopathological diagnoses: follicular non-Hodgkin lymphoma (5/14), diffuse large B-cell lymphoma (6/14) and high-grade B-cell lymphoma not otherwise specified (3/14). Six of 14 PPLs were located in the pancreatic head and 7/14 in the body-tail; 1/14 involved the whole gland. In 5/14 cases the superior mesenteric artery and vein were encased; splenic vein and artery encasement was depicted in 2 PPLs. Necrosis was present in 2/14. Enlarged retroperitoneal lymph nodes were found in 11 cases and fat stranding in all patients. The bile duct was dilated in six cases and the pancreatic duct in five. Mean neoplasm longest diameter and volume were 8.05 cm and 210.8 cm

conclusionsPPL presents as a large mass lesion with delayed homogeneous enhancement; peri-pancreatic fat stranding and vessel encasement are present, without vascular infiltration. Pancreatic duct dilatation is rare. KEY POINTS: • Primary pancreatic lymphoma (PPL) is a rare haematological disease • PPL presents imaging features in common with pancreatic carcinoma but also some distinctive findings • The majority of PPLs are large lesions with delayed homogeneous enhancement • Peri-pancreatic fat stranding and vessel encasement are common in PPL • Vascular infiltration and pancreatic duct dilatation are rare in PPL.

Indexed as

Computed tomographyDifferential diagnosisImagingLymphomaPancreas

Identifiers

PMID29335928
PMCPMC5825312
OpenAlexW2783200707

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.