ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018
A comparison of semi-automated volumetric vs linear measurement of small vestibular schwannomas.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Magnetic resonance imaging and the evaluation of vestibular schwannomas: a systematic review.Neuroradiology · 2026Pooled it
- Accuracy of vestibular schwannoma segmentation using deep learning models - a systematic review & meta-analysis.Neuroradiology · 2025Pooled it
- The impact of artificial intelligence in the diagnosis and management of acoustic neuroma: A systematic review.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Pooled it
- Evaluating growth trends of residual sporadic vestibular schwannomas: a systematic review and meta-analysis.Journal of neuro-oncology · 2022Pooled it
- Efficacy of aspirin for sporadic vestibular schwannoma: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Volumetric Assessment of Vestibular Schwannomas Exhibiting Internal Growth After Stereotactic Radiosurgery: Application of Artificial Intelligence.Clinical neuroradiology · 2026Article
- Effect of the position and volume of vestibular schwannoma on hearing threshold at diagnosis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Consensus on the use of artificial intelligence in the management and measurement of vestibular schwannomas: A protocol for a modified delphi consensus.Neuroradiology · 2026Article
- Artificial intelligence for personalized management of vestibular schwannoma: a multidisciplinary clinical implementation study.JAMIA open · 2026Article
- Clinician Perspectives of a Magnetic Resonance Imaging-Based 3D Volumetric Analysis Tool for Neurofibromatosis Type 2-Related Schwannomatosis: Qualitative Pilot Study.JMIR human factors · 2025Article
- Evaluation of Vestibular Schwannoma Size across Time: How Well Do the Experts Perform and What Can Be Improved?AJNR. American journal of neuroradiology · 2025Article
- Towards clinical implementation of automated segmentation of vestibular schwannomas: a reliability study comparing AI and human performance.Neuroradiology · 2025Article
- The Real-World Impact of Vestibular Schwannoma Fully Automated Volume Measures on the Evaluation of Size Change and Clinical Management Outcomes in a Multidisciplinary Meeting Setting.The journal of international advanced otology · 2025Article
- The development of an artificial intelligence auto-segmentation tool for 3D volumetric analysis of vestibular schwannomas.Scientific reports · 2025Article
- Defining tumor growth in vestibular schwannomas: a volumetric inter-observer variability study in contrast-enhanced T1-weighted MRI.Neuroradiology · 2024Article
- A Practical Guide to Manual and Semi-Automated Neurosurgical Brain Lesion Segmentation.NeuroSci · 2024Article
- Article
- Deep learning for automatic segmentation of vestibular schwannoma: a retrospective study from multi-center routine MRI.Frontiers in computational neuroscience · 2024Article
- Automatic segmentation of vestibular schwannomas from T1-weighted MRI with a deep neural network.Radiation oncology (London, England) · 2023Article
- Confrontation of endolymphatic hydrops diagnosis on 3-Tesla MRI to clinical and audiovestibular findings in Meniere's disease.Frontiers in neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAccurate and precise measurement of vestibular schwannoma (VS) size is key to clinical management decisions. Linear measurements are used in routine clinical practice but are prone to measurement error. This study aims to compare a semi-automated volume segmentation tool against standard linear method for measuring small VS. This study also examines whether oblique tumour orientation can contribute to linear measurement error. STUDY
designExperimental comparison of observer agreement using two measurement techniques.
settingTertiary skull base unit.
participantsTwenty-four patients with unilateral sporadic small (< 15 mm maximum intracranial dimension) VS imaged with 1 mm-thickness T1-weighted Gadolinium enhanced MRI.
main outcome measures(1) Intra and inter-observer intraclass correlation coefficients (ICC), repeatability coefficients (RC), and relative smallest detectable difference (%SDD). (2) Mean change in maximum linear dimension following reformatting to correct for oblique orientation of VS.
resultsIntra-observer ICC was higher for semi-automated volumetric when compared with linear measurements, 0.998 (95% CI 0.994-0.999) vs 0.936 (95% CI 0.856-0.972), p < 0.0001. Inter-observer ICC was also higher for volumetric vs linear measurements, 0.989 (95% CI 0.975-0.995) vs 0.946 (95% CI 0.880-0.976), p = 0.0045. The intra-observer %SDD was similar for volumetric and linear measurements, 9.9% vs 11.8%. However, the inter-observer %SDD was greater for volumetric than linear measurements, 20.1% vs 10.6%. Following oblique reformatting to correct tumour angulation, the mean increase in size was 1.14 mm (p = 0.04).
conclusionSemi-automated volumetric measurements are more repeatable than linear measurements when measuring small VS and should be considered for use in clinical practice. Oblique orientation of VS may contribute to linear measurement error.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.