Evidence map›Paper›PMID 29335679›Full record

ArticleCurrent opinion in biomedical engineering2017

Deep Tissue Imaging with Multiphoton Fluorescence Microscopy.

David R Miller, Jeremy W Jarrett, Ahmed M Hassan, Andrew K Dunn

Open access · greenAbstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
10.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 142 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

David R MillerDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton C0800, Austin, TX 78712, USA.
Jeremy W JarrettDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton C0800, Austin, TX 78712, USA.
Ahmed M HassanDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton C0800, Austin, TX 78712, USA.
Andrew K DunnDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton C0800, Austin, TX 78712, USA.
The University of Texas at Austin · US

Funding

Optical Imaging of Baseline Blood Flow and Oxygenation During StrokeR01EB011556 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K · 2010 to 2018
$3.1M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Microscale Oxygenation Mapping During StrokeR01NS082518 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K · 2013 to 2017
$1.7M
Neurovascular Mechanisms of Time-Dependencies in Stroke RehabilitationR01NS078791 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K, JONES, THERESA A · 2012 to 2016
$1.7M
An integrated imaging tool for probing EGFR subcellular trafficking in real timeR21CA193038 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K, YEH, HSIN-CHIH · 2015 to 2017
$625k
NCI NIH HHS R21 CA193038NIBIB NIH HHS R01 EB011556NIBIB NIH HHS T32 EB007507NINDS NIH HHS R01 NS078791NINDS NIH HHS R01 NS082518
6 · The paper itself

Abstract

We present a review of imaging deep-tissue structures with multiphoton microscopy. We examine the effects of light scattering and absorption due to the optical properties of biological sample and identify 1,300 nm and 1,700 nm as ideal excitation wavelengths. We summarize the availability of fluorophores for multiphoton microscopy as well as ultrafast laser sources to excite available fluorophores. Lastly, we discuss the applications of multiphoton microscopy for neuroscience.

Indexed as

Fluorophores for multiphoton microscopyLaser sources for multiphoton microscopyMultiphoton Microscopy Fluorescence ImagingScattering and absorption in brain tissue

Identifiers

PMID29335679
PMCPMC5766275
OpenAlexW2757317478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.