Evidence map›Paper›PMID 29335609›Full record

ArticleScientific reports2018

Prognostic significance of HALP (hemoglobin, albumin, lymphocyte and platelet) in patients with bladder cancer after radical cystectomy.

Ding Peng, Cui-Jian Zhang, Yan-Qing Gong, Han Hao, Bao Guan, Xue-Song Li, Li-Qun Zhou

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. A multidimensional approach to frailty in emergency surgery for perforated peptic ulcer.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Prognostic Value of HALP and PNI Scores in Predicting 6-Month Mortality Among Geriatric Hip Fracture Patients.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ding PengDepartment of Urology, Peking University First Hospital, Beijing, China.ORCID http://orcid.org/0000-0002-2252-1304
Cui-Jian ZhangDepartment of Urology, Peking University First Hospital, Beijing, China.
Yan-Qing GongDepartment of Urology, Peking University First Hospital, Beijing, China. yqgong@bjmu.edu.cn.
Han HaoDepartment of Urology, Peking University First Hospital, Beijing, China.
Bao GuanDepartment of Urology, Peking University First Hospital, Beijing, China.
Xue-Song LiDepartment of Urology, Peking University First Hospital, Beijing, China. pineneedle@sina.com.
Li-Qun ZhouDepartment of Urology, Peking University First Hospital, Beijing, China. zhoulqmail@sina.com.ORCID http://orcid.org/0000-0003-2795-9038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of bladder cancer after radical cystectomy is heterogeneous. We aim to evaluate the prognostic value of HALP (hemoglobin, albumin, lymphocyte and platelet) and explore novel prognostic indexes for patients with bladder cancer after radical cystectomy. In this retrospective study, 516 patients with bladder cancer after radical cystectomy were included. The median follow-up was 37 months (2 to 99 mo). Risk factors of decreased overall survival were older age, high TNM stage, high American Society of Anesthesiologists (ASA) grade and low HALP score. The predictive accuracy was better with HALP-based nomogram than TNM stage (C- index 0.76 ± 0.039 vs. 0.708 ± 0.041). By combining ASA grade and HALP, we created a novel index-HALPA score and found it an independent risk factor for decreased survival (HALPA score = 1, HR 1.624, 95% CI 1.139-2.314, P = 0.007; HALPA score = 2, HR 3.471, 95% CI: 1.861-6.472, P < 0.001).The present study identified the prognostic value of HALP and provided a novel index HALPA score for bladder cancer after radical cystectomy.

Indexed as

AgedAge FactorsBlood PlateletsCystectomyDisease-Free SurvivalFemaleHemoglobinsHumansKaplan-Meier EstimateLymphocytesMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesRisk FactorsHemoglobinsSerum Albumin

Identifiers

PMID29335609
PMCPMC5768698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.