Evidence map›Paper›PMID 29335491›Full record

ArticleScientific reports2018

Validation and optimization of the Systemic Inflammation-Based modified Glasgow Prognostic Score in predicting postoperative outcome of inflammatory bowel disease: preliminary data.

Chenyan Zhao, Chao Ding, Tingbin Xie, Tenghui Zhang, Xujie Dai, Yao Wei, Yi Li, Jianfeng Gong, Weiming Zhu

Open access · goldAbstract readValidation Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chenyan ZhaoDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Chao DingDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Tingbin XieDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Tenghui ZhangDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Xujie DaiDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Yao WeiDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Yi LiDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Jianfeng GongDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China. gongjianfeng@aliyun.com.
Weiming ZhuDepartment of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China. junweiming_nju@163.com.
Nanjing University · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic Inflammation-Based modified Glasgow Prognostic Score (mGPS) was developed as an objective tool to grade state of inflammation. However, the association between mGPS and postoperative complications for inflammatory bowel disease (IBD) patients was still unknown. In our study, 270 IBD patients [Crohn's disease (CD), n = 186; Ulcerative colitis (UC), n = 84] from January 2013 and January 2016 who underwent elective bowel resection were retrospectively analyzed, and, the levels of preoperative C-reactive protein (CRP) and albumin were included as parameters of mGPS. The incidence of overall postoperative complications was 44.81% (121/270), including 46.77% (87/186) of CD and 40.48% (34/84) of UC. According to multivariate analysis, mGPS (CD: OR = 3.47, p = 0.003; UC: OR = 3.28, p = 0.019) was independently associated with an increased risk of postoperative complications. Patients with a higher mGPS also suffered longer postoperative stay and increased SSIs (both p < 0.05). Combining mGPS with neutrophil ratio improved its prognostic value with a better area under the curve (AUC), using receiver operating characteristic (ROC) method. Then we confirmed that mGPS was associated with postoperative complications in IBD patients undergoing elective bowel resection and the addition of neutrophil ratio enhanced its prognostic value.

Indexed as

Decision Support TechniquesHumansIncidenceInflammatory Bowel DiseasesPostoperative ComplicationsPrognosisRetrospective StudiesROC CurveTreatment Outcome

Identifiers

PMID29335491
PMCPMC5768763
OpenAlexW2782794165

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.