ArticleScientific reports2018
Electron beam melting in the fabrication of three-dimensional mesh titanium mandibular prosthesis scaffold.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 74 citations in OpenAlex.
- Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026Review
- Integrating Machine Learning into Additive Manufacturing of Metallic Biomaterials: A Comprehensive Review.Journal of functional biomaterials · 2025Review
- A Systematic Review of the Contribution of Additive Manufacturing toward Orthopedic Applications.ACS omega · 2024Review
- The Applications of 3D-Printing Technology in Prosthodontics: A Review of the Current Literature.Cureus · 2024Review
- 3D printing titanium grid scaffold facilitates osteogenesis in mandibular segmental defects.NPJ Regenerative medicine · 2023Article
- Additively manufactured metallic biomaterials.Bioactive materials · 2022Review
- Prefabricated 3D-Printed Tissue-Engineered Bone for Mandibular Reconstruction: A Preclinical Translational Study in Primate.ACS biomaterials science & engineering · 2021Article
- Finite Element Analysis on Initial Crack Site of Porous Structure Fabricated by Electron Beam Additive Manufacturing.Materials (Basel, Switzerland) · 2021Article
- Additive manufacturing of Ti6Al4V alloy via electron beam melting for the development of implants for the biomedical industry.Heliyon · 2021Review
- Powder based additive manufacturing for biomedical application of titanium and its alloys: a review.Biomedical engineering letters · 2020Review
- Article
- Biomechanical Analysis of Various Reconstructive Methods for the Mandibular Body and Ramus Defect Using a Free Vascularized Fibula Flap.BioMed research international · 2020Article
- Additive manufacturing of bone scaffolds.International journal of bioprinting · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study was designed to fulfill effective work-flow to fabricate three-dimensional mesh titanium scaffold for mandibular reconstruction. The 3D titanium mesh scaffold was designed based on a volunteer with whole mandible defect. (1) acquisition of the CT data; (2) design with computer aided design (CAD) and finite element analysis (FEA). The pore size and intervals with the best mechanic strength was also calculated using FEA. (3) fabrication of the scaffold using electron beam melting (EBM); (4) implantation surgery. The case recovered well, without loosening and rejection. Additionally, 12 mandibular defect model beagles were used to verify the results. The model was established via tooth extraction and mandibular resection surgeries, and the scaffold was designed individually based on CT data obtained at 2 weeks after extraction operation. Then scaffolds were fabricated using 3D EBM, and the implantation surgery was performed at 2 months after extraction operation. All the animals healed well after implantation, and the grafted mandibular recovered well with time. The relevant parameters of the grafted mandibular were nearly to the native mandibular at postoperative 12 months. It is feasible to fabricate mesh titanium scaffold for repairing mandibular defects individually using reverse engineering, CAD and EBM techniques.
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Registered trials
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