ArticleScientific reports2018
Engineering Yarrowia lipolytica to Simultaneously Produce Lipase and Single Cell Protein from Agro-industrial Wastes for Feed.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 117 citations in OpenAlex.
- Yarrowia lipolytica and Komagataella phaffii (Pichia pastoris) as Hosts for Heterologous Expression of Lipases.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Tri-valorization of methanol in a single bioreactor: co-production of enzyme, chemical, and single-cell protein using engineered Pichia pastoris (Komagataella phaffii).Bioresources and bioprocessing · 2026Article
- Industrial Microbial Technologies for Feed Protein Production from Non-Protein Nitrogen.Microorganisms · 2025Review
- Preparation, purification, and biochemical of fat-degrading bacterial enzymes from pig carcass compost and its application.BMC biotechnology · 2023Article
- Trends in the Use of Lipases: A Systematic Review and Bibliometric Analysis.Foods (Basel, Switzerland) · 2023Review
- The microbial food revolution.Nature communications · 2023Review
- Sugar Beet Pulp as a Biorefinery Substrate for Designing Feed.Molecules (Basel, Switzerland) · 2023Article
- High-yield α-humulene production in Yarrowia lipolytica from waste cooking oil based on transcriptome analysis and metabolic engineering.Microbial cell factories · 2022Article
- New roles for Yarrowia lipolytica in molecules synthesis and biocontrol.Applied microbiology and biotechnology · 2022Review
- Lipid production from lignocellulosic biomass using an engineered Yarrowia lipolytica strain.Microbial cell factories · 2022Article
- Effect of AutolyzedInternational journal of molecular sciences · 2022Article
- Single-Cell Proteins Obtained by Circular Economy Intended as a Feed Ingredient in Aquaculture.Foods (Basel, Switzerland) · 2022Review
- Review
- Comprehensive utilization of palm kernel cake for producing mannose and manno-oligosaccharide mixture and yeast culture.Applied microbiology and biotechnology · 2022Article
- Yeast Protein as an Easily Accessible Food Source.Metabolites · 2022Review
- Application of a New Engineered Strain ofInternational journal of molecular sciences · 2021Article
- Review
- Expression of novel acidic lipase from Micrococcus luteus in Pichia pastoris and its application in transesterification.Journal, genetic engineering & biotechnology · 2021Article
- Microbiota profiling and screening of the lipase active halotolerant yeasts of the olive brine.World journal of microbiology & biotechnology · 2021Article
- Sustainable production of FAEE biodiesel using the oleaginous yeast Yarrowia lipolytica.MicrobiologyOpen · 2020Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipases are scarcely exploited as feed enzymes in hydrolysis of lipids for increasing energy supply and improving nutrient use efficiency. In this work, we performed homologous overexpression, in vitro characterization and in vivo assessment of a lipase from the yeast Yarrowia lipolytica for feed purpose. Simultaneously, a large amount of yeast cell biomass was produced, for use as single cell protein, a potential protein-rich feed resource. Three kinds of low cost agro-industrial wastes were tested as substrates for simultaneous production of lipase and single cell protein (SCP) as feed additives: sugarcane molasses, waste cooking oil and crude glycerol from biodiesel production. Sugarcane molasses appeared as the most effective cheap medium, allowing production of 16420 U/ml of lipase and 151.2 g/L of single cell protein at 10 liter fermentation scale. In vitro characterization by mimicking a gastro-intestinal environment and determination of essential amino acids of the SCP, and in vivo oral feeding test on fish all revealed that lipase, SCP and their combination were excellent feed additives. Such simultaneous production of this lipase and SCP could address two main concerns of feed industry, poor utilization of lipid and shortage of protein resource at the same time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.