ArticleScientific reports2018
RFA Guardian: Comprehensive Simulation of Radiofrequency Ablation Treatment of Liver Tumors.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Clinical evaluation of in silico planning and real-time simulation of hepatic radiofrequency ablation (ClinicIMPPACT Trial).European radiology · 2020Trial
- Spatial Porosity as a Diagnostic Predictor of Conductivity Collapse in Patient-Specific Radiofrequency Ablation of Liver Tumors.Diagnostics (Basel, Switzerland) · 2026Article
- Intercostal Nerve Radiofrequency Ablation: A Comprehensive Review of Evolving Techniques and Clinical Applications.Advances in therapy · 2026Review
- Point cloud registration algorithm using liver vascular skeleton feature with computed tomography and ultrasonography image fusion.International journal of computer assisted radiology and surgery · 2025Article
- Gradual Temperature Rise in Radiofrequency Ablation: Enhancing Lesion Quality and Safety in Porcine Myocardial Tissue.Bioengineering (Basel, Switzerland) · 2025Article
- Review
- First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset.Scientific reports · 2023Article
- Tips for Preparing and Practicing Thermal Ablation Therapy of Hepatocellular Carcinoma.Cancers · 2023Review
- Optimization of laser dosimetry based on patient-specific anatomical models for the ablation of pancreatic ductal adenocarcinoma tumor.Scientific reports · 2023Article
- Model-based hepatic percutaneous microwaveablation planning. First validation on a clinical dataset.Research square · 2023Article
- Validation of Software for Patient-Specific Real-Time Simulation of Hepatic Radiofrequency Ablation.Academic radiology · 2022Article
- Microwave ablation of lung tumors: A probabilistic approach for simulation-based treatment planning.Medical physics · 2021Article
- Software-based planning of ultrasound and CT-guided percutaneous radiofrequency ablation in hepatic tumors.International journal of computer assisted radiology and surgery · 2021Article
- Therapeutic Systems and Technologies: State-of-the-Art Applications, Opportunities, and Challenges.IEEE reviews in biomedical engineering · 2020Review
- Can tumor coverage evaluated 24 h post-radiofrequency ablation predict local tumor progression of liver metastases?International journal of computer assisted radiology and surgery · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The RFA Guardian is a comprehensive application for high-performance patient-specific simulation of radiofrequency ablation of liver tumors. We address a wide range of usage scenarios. These include pre-interventional planning, sampling of the parameter space for uncertainty estimation, treatment evaluation and, in the worst case, failure analysis. The RFA Guardian is the first of its kind that exhibits sufficient performance for simulating treatment outcomes during the intervention. We achieve this by combining a large number of high-performance image processing, biomechanical simulation and visualization techniques into a generalized technical workflow. Further, we wrap the feature set into a single, integrated application, which exploits all available resources of standard consumer hardware, including massively parallel computing on graphics processing units. This allows us to predict or reproduce treatment outcomes on a single personal computer with high computational performance and high accuracy. The resulting low demand for infrastructure enables easy and cost-efficient integration into the clinical routine. We present a number of evaluation cases from the clinical practice where users performed the whole technical workflow from patient-specific modeling to final validation and highlight the opportunities arising from our fast, accurate prediction techniques.
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Registered trials
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