SynthesisJournal of the American Heart Association2018
Longitudinal Effect of Stroke on Cognition: A Systematic Review.
Synthesis in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05951530 (The Impact of App-based Cognitive Training on Post-stroke Upper Extremity Rehabilitation), which is not on this map. Cited by 83 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of App-based Cognitive Training on Post-stroke Upper Extremity Rehabilitation
Who cites it
83 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Pooled it
- Digital Interventions for Cognitive Dysfunction in Patients With Stroke: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Cognitive impairment after a stroke in young adults: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Short-term Trajectories of Poststroke Cognitive Function: A STROKOG Collaboration Study.Neurology · 2023Pooled it
- Fire Acupuncture versus conventional acupuncture to treat spasticity after stroke: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Can we prevent poststroke cognitive impairment? An umbrella review of risk factors and treatments.BMJ open · 2020Pooled it
- Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study.PLoS medicine · 2019Pooled it
- Anticoagulation in atrial fibrillation and cognitive decline: A systematic review and meta-analysis.Medicine · 2019Pooled it
- A randomized controlled trial of online mindfulness-based stress reduction in chronic stroke.Rehabilitation psychology · 2026Trial
- Change in Cognition Following Ischaemic Stroke.Annals of clinical and translational neurology · 2026Trial
- Early sleep apnea treatment in stroke (eSATIS) - a multicentre, randomised controlled, rater-blinded, clinical trial: The association of post-stroke cognition with sleep-disordered breathing and its treatment.Journal of sleep research · 2025Trial
- A prospective cohort study on longitudinal trajectories of cognitive function after stroke.Scientific reports · 2021Trial
- A comparison of two personalization and adaptive cognitive rehabilitation approaches: a randomized controlled trial with chronic stroke patients.Journal of neuroengineering and rehabilitation · 2020Trial
- Dysfunction of hippocampal cells and its role in cognitive impairment.Neural regeneration research · 2026Article
- Longitudinal Trajectories of Global and Domain-Specific Cognition After Stroke Using the Oxford Cognitive Screen.Stroke · 2026Article
- Feasibility of identifying factors related to Alzheimer's disease and related dementia in real-world data.JAMIA open · 2026Review
- Serum Creatinine Clearance and Cognitive Function in Older Adults: Mediating Effects of Systemic Inflammatory Response Index.Brain and behavior · 2026Article
- Cardiometabolic risk mediates the association between perceived stress and learning and memory similarly among Hispanic/Latino and non-Hispanic White individuals.Journal of clinical and experimental neuropsychology · 2026Observational
- Comparison of cognitive decline rates and risk factors between stroke and non - stroke populations: An analysis of data from the China health and retirement longitudinal study (CHARLS).Cerebral circulation - cognition and behavior · 2026Article
- Association Between Carotid Atherosclerosis and Post-Stroke Cognitive Impairment in Patients With Mild Ischemic Stroke: A Prospective Cohort Study.CNS neuroscience & therapeutics · 2026Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundStroke is associated with an increased risk of dementia; however, the impact of stroke on cognition has been found to be variable, such that stroke survivors can show decline, remain stable, or revert to baseline cognitive functioning. Knowing the natural history of cognitive impairment after stroke is important for intervention. The aim of this systematic review is to investigate the longitudinal course of cognitive function in stroke survivors. METHODS AND
resultsThree electronic databases (Medline, Embase, PsycINFO) were searched using OvidSP from inception to July 15, 2016. Longitudinal studies with ≥2 time points of cognitive assessment after stroke were included. In total, 5952 articles were retrieved and 14 were included. There was a trend toward significant deterioration in cognitive test scores in stroke survivors (8 studies). Cognitive stability (3 studies) and improvement (3 studies) were also demonstrated, although follow-up time tended to be shorter in these studies. Variables associated with impairment included age, ethnicity, premorbid cognitive performance, depression, stroke location, and history of previous stroke. Associations with
conclusionsStroke is associated with an increased risk of cognitive decline, but cognitive decline is not a consequence. Factors associated with decline, such as sociodemographic status, health-related comorbidity, stroke history, and clinical features could be used in models to predict future risk of dementia after stroke. A risk model approach could identify patients at greatest risk for timely intervention to reduce the frequency or delay the onset of poststroke cognitive impairment and dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.