ArticleCirculation. Cardiovascular imaging2018
Complementary Value of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography/Computed Tomography in the Assessment of Cardiac Sarcoidosis.
Open access · bronzeAbstract read
In one paragraph
Article in Circulation. Cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 2 pooled it
17.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 2 syntheses or guidelines pooled it, 263 citations in OpenAlex.
- Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Cardiac Magnetic Resonance Imaging for Diagnosis of Cardiac Sarcoidosis: A Meta-Analysis.Canadian respiratory journal · 2018Pooled it
- The Role of Hybrid PET-MRI in the Diagnosis and Management of Cardiac Sarcoidosis-A Narrative Review.Journal of clinical medicine · 2026Review
- Diagnostic and prognostic value of T2 mapping in cardiac sarcoidosis.International journal of cardiology. Heart & vasculature · 2026Article
- Diagnostic challenges in isolated cardiac sarcoidosis.ESC heart failure · 2026Review
- Article
- From guidelines to reality: how do physicians really manage sarcoidosis?BMC pulmonary medicine · 2026Article
- Multiparametric CMR in Myocarditis: A Comprehensive Review of Diagnostic Advances, Prognostic Value, and the Challenge of Genetic Mimics.Biomedicines · 2026Review
- Beyond the Biopsy: Imaging Frontiers in Cardiac Sarcoidosis.Cardiology research and practice · 2026Review
- Severe Acute Decompensated Heart Failure in a Patient with Cardiac Sarcoidosis.Journal of clinical medicine · 2025Article
- Cardiac sarcoidosis: The role of steroid therapy in managing myocardial inflammation and arrhythmic risks.World journal of cardiology · 2025Review
- Diagnoses and outcomes of patients referred for FDG PET/CT for suspected cardiac sarcoidosis.International journal of cardiology · 2025Article
- Updates on Cardiac MRI and PET Imaging for the Diagnosis and Monitoring of Cardiac Sarcoidosis.Korean journal of radiology · 2025Review
- Toward optimal inline respiratory motion correction for in vivo cardiac diffusion tensor MRI using symmetric and inverse-consistent deformable image registration.Magnetic resonance in medicine · 2025Article
- Myocardial-to-background ratio in F18-fluorodeoxyglucose PET in cardiac sarcoidosis for diagnosis and evaluation of therapeutic response.International journal of cardiology. Heart & vasculature · 2025Article
- Cardiac Magnetic Resonance Imaging in the Evaluation and Prognosis of Infiltrative Cardiomyopathies.Journal of cardiovascular development and disease · 2025Review
- Screening for cardiac sarcoidosis: diagnostic approach and long-term follow-up in a tertiary centre.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Acute Myocarditis and Inflammatory Cardiomyopathies: Insights From Cardiac Magnetic Resonance Findings.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Magnetic Resonance Imaging in the Assessment of the Risk of Sudden Death in Cardiac Sarcoidosis: What Is Extensive or Significant Late Gadolinium Enhancement?Circulation. Arrhythmia and electrophysiology · 2025Article
- Cardiovascular Information and Health Engineering Medicine.Research (Washington, D.C.) · 2025Review
65 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
16 authors at 3 institutions in 1 country.
Tomas VitaFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
David R OkadaFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Mahdi Veillet-ChowdhuryFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Paco E BravoFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Erin MullinsFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Edward HultenFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Mukta AgrawalFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Rachna MadanFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Viviany R TaquetiFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Michael SteignerFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Hicham SkaliFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Raymond Y KwongFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Garrick C StewartFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Sharmila DorbalaFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Marcelo F Di CarliFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.).
Ron BlanksteinFrom the Cardiovascular Division, Department of Medicine, Cardiovascular Imaging Program (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Department of Radiology (T.V., M.V.-C., P.E.B., E.M., E.H., V.R.T., M.S., H.S., R.Y.K., S.D., M.F.D.C., R.B.), Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (M.A., S.D., M.F.D.C., R.B.), Division of Thoracic Radiology, Department of Radiology (R.M.), and Cardiovascular Division (H.S., R.Y.K., G.S., M.F.D.C., R.B.), Brigham and Women's Hospital, Boston, MA; Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD (D.R.O.); Division of Medicine, Cardiology Service, Walter Reed National Military Medical Center, Bethesda, MD (E.H.); and Uniformed Services University of Health Sciences, Bethesda, MD (E.H.). rblankstein@bwh.harvard.edu.
Brigham and Women's Hospital · USWalter Reed National Military Medical Center · USJohns Hopkins Hospital · US
Funding
Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8MNHLBI NIH HHS T32 HL094301
Abstract
backgroundAlthough cardiac magnetic resonance (CMR) and positron emission tomography (PET) detect different pathological attributes of cardiac sarcoidosis (CS), the complementary value of these tests has not been evaluated. Our objective was to determine the value of combining CMR and PET in assessing the likelihood of CS and guiding patient management. METHODS AND
resultsIn this retrospective study, we included 107 consecutive patients referred for evaluation of CS by both CMR and PET. Two experienced readers blinded to all clinical data reviewed CMR and PET images and categorized the likelihood of CS as no (<10%), possible (10%-50%), probable (50%-90%), or highly probable(>90%) based on predefined criteria. Patient management after imaging was assessed for all patients and across categories of increasing CS likelihood. A final clinical diagnosis for each patient was assigned based on a subsequent review of all available imaging, clinical, and pathological data. Among 107 patients (age, 55±11 years; left ventricular ejection fraction, 43±16%), 91 (85%) had late gadolinium enhancement, whereas 82 (76%) had abnormal F18-fluorodeoxyglucose uptake on PET, suggesting active inflammation. Among the 91 patients with positive late gadolinium enhancement, 60 (66%) had abnormal F18-fluorodeoxyglucose uptake. When PET data were added to CMR, 48 (45%) patients were reclassified as having a higher or lower likelihood of CS, most of them (80%) being correctly reclassified when compared with the final diagnosis. Changes in immunosuppressive therapies were significantly more likely among patients with highly probable CS.
conclusionsAmong patients with suspected CS, combining CMR and PET provides complementary value for estimating the likelihood of CS and guiding patient management.
Indexed as
Magnetic Resonance ImagingPositron Emission Tomography Computed TomographyAgedCardiomyopathiesContrast MediaFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesSarcoidosisContrast MediaFluorodeoxyglucose F18Radiopharmaceuticalsdiagnosisheart failureinflammationsarcoidosis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.