ArticleBiomedical engineering online2018
Generalized estimation of the ventilatory distribution from the multiple-breath washout: a bench evaluation study.
Article in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
backgroundThe multiple-breath washout (MBW) is able to provide information about the distribution of ventilation-to-volume (v/V) ratios in the lungs. However, the classical, all-parallel model may return skewed results due to the mixing effect of a common dead space. The aim of this work is to examine whether a novel mathematical model and algorithm is able to estimate v/V of a physical model, and to compare its results with those of the classical model. The novel model takes into account a dead space in series with the parallel ventilated compartments, allows for variable tidal volume (V
methodsTwo physical models with preset v/V units and a common series dead space (v
resultsThe v/V distributions estimated with constrained EELV and V
conclusionsThe proposed model and algorithm provided better estimates of v/V than the classical model, particularly with constrained V
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