ArticleBMC nephrology2018
Association of Kidney Disease Quality of Life (KDQOL-36) with mortality and hospitalization in older adults receiving hemodialysis.
Article in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Impact of chronic kidney disease on adults and their caregivers in the United States: a systematic literature review.BMC nephrology · 2026Pooled it
- Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis.BMC nephrology · 2020Pooled it
- Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis.Health and quality of life outcomes · 2020Pooled it
- Predictors of quality of life in patients within the first year of commencing haemodialysis based on baseline data from the PIVOTAL trial and associations with the study outcomes.Journal of nephrology · 2023Trial
- Trial
- Symptom Burden After Dialysis Initiation and Its Association With Hospitalization.Kidney medicine · 2026Article
- Functional Predictors of Frailty and Kidney Disease Burden in Patients with End-stage Renal Disease Receiving Dialysis.Journal of frailty, sarcopenia and falls · 2026Article
- Examining Quality-of-Life Priorities of Older Adults Receiving Hemodialysis: A Q-Methodology Study.Kidney medicine · 2026Article
- A systematic review and meta-analysis and mendelian randomization analysis of serum phosphorus, albumin, and CRP as risk factors for death in hemodialysis patients.Journal of medical biochemistry · 2026Article
- Factors associated with survival among patients with end-stage kidney disease undergoing hemodialysis in Tanzania: a cohort study.BMC nephrology · 2026Article
- Loneliness in Older Adults Receiving Hemodialysis and Associated Factors: A Cross-Sectional Study.The journal of nursing research : JNR · 2025Article
- Physical Domains, Access to Kidney Transplantation, and Waitlist Mortality.Clinical transplantation · 2025Article
- Article
- Psychometric properties of the Kidney Disease Quality of Life short form 36 (KDQOL-36) scale for the assessment of quality of life in Colombian patients with chronic kidney disease on dialysis.International urology and nephrology · 2024Article
- Article
- Frailty in middle-aged and older adult postoperative patients with gynecological malignancies structural equation modeling.Frontiers in public health · 2024Article
- Article
- Effectiveness of Acupuncture on Health-Related Quality of Life in Patients Receiving Maintenance Hemodialysis.Healthcare (Basel, Switzerland) · 2023Article
- Cognitive Impairment, Frailty, and Adverse Outcomes Among Prevalent Hemodialysis Recipients: Results From a Large Prospective Cohort Study in the United Kingdom.Kidney medicine · 2023Article
- Is malnutrition a determining factor of health-related quality of life in hemodialysis patients? A cross-sectional design examining relationships with a comprehensive assessment of nutritional status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundFor older adults receiving dialysis, health-related quality of life is not often considered in prognostication of death or future hospitalizations. To determine if routine health-related quality of life measures may be useful for prognostication, the objective of this study is to determine the extent of association of Kidney Disease Quality of Life (KDQOL-36) subscales with adverse outcomes in older adults receiving dialysis.
methodsThis is a longitudinal study of 3500 adults aged ≥75 years receiving dialysis in the United States in 2012 and 2013. We used Cox and Fine and Gray models to evaluate the association of KDQOL-36 subscales with risk of death and hospitalization. We adjusted for sociodemographic variables, hemodialysis access type, laboratory values, and Charlson index.
resultsThree thousand one hundred thirty-two hemodialysis patients completed the KDQOL-36. From KDQOL-36 completion date in 2012, 880 (28.1%) died and 2023 (64.6%) had at least one hospitalization over a median follow-up of 512 and 203 days, respectively. Cohort members with a SF-12 physical component summary (PCS) in the lowest quintile had an increased adjusted risk of death [hazard ratio (HR), 1.55, 95% confidence interval (CI) 1.19-2.03] and hospitalization (HR, 1.29, 95% CI 1.09-1.54) compared with those with scores in the highest quintile. Cohort members with a SF-12 mental component summary in the lowest quintile had an increased risk of hospitalization (HR, 1.39, 95% CI 1.17-1.65) compared with those in the highest quintile. In adjusted analyses, there was no association between the symptoms of kidney disease, effects of kidney disease, and burden of kidney disease subscales with time to death or first hospitalization. Competing risk models showed similar HRs.
conclusionsAmong the KDQOL-36 subscales, the SF-12 PCS demonstrates the strongest association with both death and future hospitalizations in older adults receiving hemodialysis Further research is needed to assess the value this subscale may add to prognostication.
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